Childhood BMI and other measures of body composition as a predictor of cardiometabolic non-communicable diseases in adulthood: a systematic review.
Childhood BMI and other measures of body composition as a predictor of cardiometabolic non-communicable diseases in adulthood: a systematic review.
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儿童体重指数和其他身体成分测量作为成年期心脏代谢非传染性疾病的预测因子：系统评价。
DOI：
10.1017/s136898002200235x
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发表时间：
2022
影响因子：
3.2
通讯作者：
Bander A
中科院分区：
文献类型：
--
作者：
Bander A
越来越多的证据表明，儿童营养不良与成年后的非传染性疾病（NCD）有关，身体成分介导了这种关联。本综述旨在确定儿童期身体成分是否可用于预测以后的心血管代谢NCD，以及哪些身体成分指标可预测未来的NCD.DesignElectronic数据库中的文章，其中：5岁以下儿童的身体成分测量;至少在10年后测量心脏代谢健康结果。检索Medline和Global Health数据，截止2020年7月。研究对象为5岁以下儿童，随访时间至少为10年。尽管身体组成的替代指标较差，但通常报告体重指数（BMI）（n 28，97%）。这些研究中有25%包括额外的测量（重量指数或皮褶厚度）。很少有研究调整目前的身体大小（n 11，39%）。ConclusionsMany studies reported that low infant BMI and high childhood BMI are associated with a increased risk of NCD related outcomes in later life but no conclusions can be made about the确切的时间儿童营养不良和随之而来的影响NCD。由于研究的重点是体重指数，而不是身体成分的直接措施，没有什么可以说，在儿童时期的身体成分的措施是最有用的。未来对儿童营养和长期结果的研究是迫切需要的，应该包括有效的身体成分评估以及标准的人体测量和BMI测量。
ObjectiveThere is growing evidence that childhood malnutrition is associated with non-communicable diseases (NCD) in adulthood and that body composition mediates some of this association. This review aims to determine if childhood body composition can be used to predict later-life cardiometabolic NCD and which measures of body composition predicts future NCD.DesignElectronic databases were searched for articles where: children aged under 5 years had body composition measured; cardiometabolic health outcomes were measured a minimum of 10 years later.SettingThe databases Embase, Medline and Global Health were searched through July 2020.ParticipantsChildren aged under 5 years with a follow-up of minimum 10 years.ResultsTwenty-nine studies met the inclusion criteria. Though a poor proxy measure of body composition, body mass index (BMI) was commonly reported (n 28, 97 %). 25 % of these studies included an additional measure (ponderal index or skinfold thickness). Few studies adjusted for current body size (n 11, 39 %).ConclusionsMany studies reported that low infant BMI and high childhood BMI were associated with an increased risk of NCD-related outcomes in later life but no conclusions can be made about the exact timing of child malnutrition and consequent impact on NCD. Because studies focussed on BMI rather than direct measures of body composition, nothing can be said about which measures of body composition in childhood are most useful. Future research on child nutrition and long-term outcomes is urgently needed and should include validated body composition assessments as well as standard anthropometric and BMI measurements.