SEMMES-WEINSTEIN MONOFILAMENTS - A SIMPLE, EFFECTIVE AND INEXPENSIVE SCREENING DEVICE FOR IDENTIFYING DIABETIC-PATIENTS AT RISK OF FOOT ULCERATION
SEMMES-WEINSTEIN MONOFILAMENTS - A SIMPLE, EFFECTIVE AND INEXPENSIVE SCREENING DEVICE FOR IDENTIFYING DIABETIC-PATIENTS AT RISK OF FOOT ULCERATION
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DOI：
10.1016/0168-8227(91)90034-b
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发表时间：
1991-01-01
影响因子：
5.1
通讯作者：
BOULTON, AJM
中科院分区：
文献类型：
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作者：
KUMAR, S;FERNANDO, DJS;BOULTON, AJM
已提出通过生物电测法测定振动感知阈值 (VPT) 和使用 Semmes-Weinstein 单丝（细丝）的压力感知来识别有足部溃疡风险的糖尿病患者。 在参加全国患者会议的 182 名受试者中对这两种方法进行了比较。 两项测量均针对大脚趾进行。 使用三种口径的细丝：分别用1、10和75克力弯曲4.17、5.07和6.10。 122 名患者（第 1 组）的压力感知正常（4.17），而 45 名患者（第 2 组）的压力感知为 5.07 级，15 名患者（第 3 组）的压力感知为 6.10 或更高。 三组相应的平均 VPT (+/- SD) 分别为 10.6 (+/- 6.7)、22.8 (+/- 12.7) 和 32 (+/- 14.3)。 3 组的平均 VPT 显着不同 (P < 0.001)。 与敏感度较低（78.6%）但特异性较高（93.4%）的生物电测法相比，丝线在识别足部溃疡患者方面更敏感（100%），但特异性较差（77.7%）。 因此，在筛查有足部溃疡风险的患者时，细丝是可靠的，并且可能优于生物电测法，因为敏感性是更重要的参数。 此外，与生物感觉计（400 英镑）相比，它们价格便宜（12 英镑），并且简单易用。
Both vibration perception threshold (VPT) by biothesiometry and pressure perception using Semmes-Weinstein monofilaments (filaments) have been proposed to identify diabetic patients at risk of foot ulceration. The two methods were compared in 182 subjects attending a national patients conference. Both measures were made over the great toe. Filaments of three calibres were used: 4.17, 5.07 and 6.10 bending with 1, 10 and 75 g force, respectively. Pressure perception was normal (4.17) in 122 patients (group 1) whereas in 45 patients it was grade 5.07 (group 2) and 6.10 or greater in 15 (group 3). The corresponding mean VPT (+/- SD) for the three groups were 10.6 (+/- 6.7), 22.8 (+/- 12.7) and 32 (+/- 14.3), respectively. The mean VPT for the 3 groups were significantly different (P < 0.001). The filaments were more sensitive (100%) but less specific (77.7%) in identifying patients who had foot ulcers compared to biothesiometry which was less sensitive (78.6%) but more specific (93.4%). The filaments are therefore reliable and may be superior to biothesiometry in screening for patients at risk of foot ulceration since sensitivity is the more important parameter. In addition, they are inexpensive (12 pound sterling) compared to the biothesiometer (400 pound sterling) and are simple and easy to use.