Structure of schizophrenic symptomatology and its changes over time: prospective factor‐analytical study
Structure of schizophrenic symptomatology and its changes over time: prospective factor‐analytical study
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精神分裂症症状的结构及其随时间的变化：前瞻性因素分析研究
DOI：
10.1111/j.1600-0447.1997.tb00370.x
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发表时间：
1997
影响因子：
6.7
通讯作者：
R. Salokangas
中科院分区：
文献类型：
--
作者：
R. Salokangas
在首次接触精神病治疗时，对156例新发精神分裂症患者（DSM-III）的代表性样本进行了检查，并在2年和5年后进行了复查。采用综合精神病理评定量表（CPRS）评估症状变量，并相互比较。以下主要维度被发现：（i）一个相当稳定的负面维度，伴随着情感和言语的压抑和退缩;（ii）一个妄想维度;（iii）幻觉维度;（iv）一个混乱维度;（v）一个抑郁维度，伴随着不真实的经历。未婚患者的消极维度更普遍。无论是消极和积极症状的两种综合征模型，还是精神贫困、混乱和现实扭曲的三种综合征模型，都不能令人满意。在精神分裂症患者的代表性样本中，由症状维度描述的综合征结构似乎更复杂，并且根据疾病的持续时间而变化很大。
A representative sample of 156 new schizophrenic patients (DSM‐III) were examined at the time of their first treatment contact for psychosis, and reexamined 2 and 5 years thereafter. The symptom variables, assessed by the Comprehensive Psychopathological Rating Scale (CPRS), were factored and compared with each other. The following major dimensions were found: (i) a fairly stable negative dimension with affective and speech impoverishment and withdrawal; (ii) a delusional dimension; (iii) hallucinatory dimensions; (iv) a disorganization dimension; and (v) a depressive dimension with unreal experiences. The negative dimension was more prevalent in unmarried patients. Neither the two‐syndrome model of negative and positive symptoms nor the three‐syndrome model of psychomotor poverty, disorganization and reality distortion proved to be satisfactory. In a representative sample of schizophrenic patients, the syndrome structure described by symptom dimensions appears to be more complex and varies considerably according to the duration of the illness.