Use of food quotients to predict respiratory quotients for the doubly-labelled water method of measuring energy expenditure.
Use of food quotients to predict respiratory quotients for the doubly-labelled water method of measuring energy expenditure.
复制标题
使用食物商来预测呼吸商，用于测量能量消耗的双标记水方法。
DOI：
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
W. Coward
中科院分区：
文献类型：
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作者：
A. Black;A. Prentice;W. Coward
本文提出了一种估算用双标记水技术测定人体自由生活能量消耗时所需呼吸量的方法。工作实例表明，在大多数正常人中，由于能量平衡通常在10-20天的双同位素测量期间得以维持，因此可以用测定或预测的食物量代替呼吸量。在英国观察到的荧光定量的例子是：杂食性成年人，0.845 +/- 0.013（标准差）;素食者、严格素食者和亚洲移民，0.860-0.880;母乳喂养的婴儿，0.835随着断奶的进展上升到0.870;奶瓶喂养的婴儿，0.840-0.880。酒精摄入量超过总能量的2- 3%会降低FQ值。在发展中国家的大多数社区中，由于脂肪对总能量摄入的贡献较低，因此脂肪质量要高得多（0.900-0.955）;但随着饮食变得更加西化，脂肪质量逐渐下降。在英国，基于4-d加权摄入量的受试者间和受试者内变异系数分别仅为1.5%和0.7%。因此，饮食组成的单个4-d测量可用于预测受试者的FQ。在能量不平衡的受试者中（例如，在生长、疾病或节食期间），即使忽略不平衡，计算的能量消耗的误差也很少超过3- 5%;在实践中，可以考虑厌食症或卡替病，并在将FQ转换为RQ时调整FQ。在双标记水方法中，由于用调整后的FQ代替RQ而产生的误差通常可以忽略不计，不应超过+/-2%。
A method is proposed for estimating the respiratory quotients (RQ) required in the calculation of free-living energy expenditure measured by the doubly-labelled water technique in man. Worked examples show that, in most normal subjects, measured or predicted food quotients (FQ) can be used in place of RQs since energy balance is usually maintained over the 10-20-d periods of double-isotope measurements. Examples of observed FQs in the UK are: omnivorous adults, 0.845 +/- 0.013 (s.d.); vegetarians, vegans and Asian immigrants, 0.860-0.880; breast-fed infants, 0.835 rising to 0.870 as weaning progresses; bottle-fed infants, 0.840-0.880. Alcohol intakes in excess of 2-3 per cent of total energy lower the FQ value. In most communities in the developing world FQs are substantially higher (0.900-0.955) due to the low contribution of fat to overall energy intakes; but FQs decrease progressively as the diet becomes more westernized. In the UK the between- and within-subject coefficients of variation based on 4-d weighed intakes are only 1.5 and 0.7 per cent respectively. A single 4-d measurement of dietary composition can therefore be used to predict a subject's FQ. In subjects in energy imbalance (eg, during growth, illness or when dieting) errors in calculated energy expenditure will rarely exceed 3-5 per cent even if the imbalance is ignored; in practice anabolism or catabolism can be accounted for and the FQ adjusted when converting FQ to RQ. The error incurred due to the substitution of adjusted FQ for RQ in the doubly-labelled water method will usually be negligible and should never exceed +/- 2 per cent.