Myocardial viability by contrast-enhanced cardiovascular magnetic resonance in patients with coronary artery disease: comparison with gated single-photon emission tomography and FDG position emission tomography
Myocardial viability by contrast-enhanced cardiovascular magnetic resonance in patients with coronary artery disease: comparison with gated single-photon emission tomography and FDG position emission tomography
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DOI：
10.1007/s10554-007-9215-y
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发表时间：
2007-12-01
影响因子：
2.1
通讯作者：
Togashi, Kaori
中科院分区：
文献类型：
--
作者：
Wu, Yen-Wen;Tadamura, Eiji;Togashi, Kaori
背景 本研究的目的是评估对比增强心血管磁共振 (CMR) 对冠状动脉疾病和左心室 (LV) 功能障碍（射血分数 [EF] = 50% 最大 Tl-201 活性）患者生存能力的价值，CMR (>= 50% DE) 为 96.8% (kappa = 0.62)。 CMR 在 18 名受试者（60 个节段）中检测到更多心内膜下疤痕。在 19 名受试者（76 个节段；更下）中观察到 Tl-201 活性降低，但没有观察到 DE，这些受试者的 EF 较低，收缩末期容积较大（p < 0.05）。在 46 名患者的 411 个功能障碍节段中，FDG-PET（>= 最大 FDG 摄取的 50%）检测到更多活力 (9%)。 结论 DE 程度与 Tl-201 活性良好相关。 CMR 可以检测更多的小梗塞，而 FDG-PET 可以检测更多的存活率。 CMR 可以区分 SPECT 上的伪影或梗塞，尤其是在 LV 功能较差的情况下。
Background The aim of this study was to assess the value of contrast-enhanced cardiovascular magnetic resonance (CMR) in viability for patients with coronary artery disease and left ventricular (LV) dysfunction (ejection fraction [EF] = 50% maximal Tl-201 activity) and CMR (>= 50% DE) was 96.8% (kappa = 0.62). CMR detected more subendocardial scars in 18 subjects (60 segments). Reduced Tl-201 activity but none DE were observed in 19 subjects (76 segments; more inferior) who had lower EF and larger end-systolic volume (p < 0.05). Of 411 dysfunctional segments from 46 patients, FDG-PET (>= 50% of maximal FDG uptake) detected more viability (9%).Conclusion The extent of DE correlated Tl-201 activity well. CMR could detect more small infarcts, while FDG-PET could detect more viability. CMR could distinguish between artifacts or infarction on SPECT, especially in poor LV function.