Phase entrainment of human delta oscillations can mediate the effects of expectation on reaction speed.
Phase entrainment of human delta oscillations can mediate the effects of expectation on reaction speed.
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人类三角洲振荡的相位夹带可以介导期望对反应速度的影响。
DOI：
10.1523/jneurosci.0703-10.2010
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发表时间：
2010-10-13
期刊：
影响因子：
--
通讯作者：
Ulbert I
中科院分区：
文献类型：
--
作者：
Stefanics G;Hangya B;Hernádi I;Winkler I;Lakatos P;Ulbert I
我们对可预测刺激的反应预期越多，我们的反应就越快。这一经验性的观察结果已经被许多研究者证实和量化，这表明基于概率的预期信心促进了行为相关刺激的处理。然而，这种现象背后的确切神经机制在很大程度上是未知的。在这里，我们表明，性能变化相关的不同水平的期望起源于动态调制的三角洲振荡相位。我们的研究结果表明，在有节奏的听觉目标检测任务中，显著夹带的EEG三角洲节奏的目标音调的发病，增加相位同步在较高水平的可预测性。反应时间与目标开始时δ带振荡的相位相关。最快的反应发生在δ期，在高期望条件下最常与目标事件相吻合。这些结果表明，低频振荡在人类预期机制中发挥着功能性作用，可能是通过调节大型神经元群体兴奋性的同步节奏波动，以及通过促进负责感觉处理和响应执行的脑区之间的有效任务相关神经元通信。
The more we anticipate a response to a predictable stimulus, the faster we react. This empirical observation has been confirmed and quantified by many investigators suggesting that the processing of behaviorally relevant stimuli is facilitated by probability-based confidence of anticipation. However, the exact neural mechanisms underlying this phenomenon are largely unknown. Here we show that performance changes related to different levels of expectancy originate in dynamic modulation of delta oscillation phase. Our results obtained in rhythmic auditory target detection tasks indicated significant entrainment of the EEG delta rhythm to the onset of the target tones with increasing phase synchronization at higher levels of predictability. Reaction times correlated with the phase of the delta band oscillation at target onset. The fastest reactions occurred during the delta phase that most commonly coincided with the target event in the high expectancy conditions. These results suggest that low-frequency oscillations play a functional role in human anticipatory mechanisms, presumably by modulating synchronized rhythmic fluctuations in the excitability of large neuronal populations and by facilitating efficient task-related neuronal communication among brain areas responsible for sensory processing and response execution.