Stimulation of glucose transport by thyroid hormone in 3T3-L1 adipocytes: increased abundance of GLUT1 and GLUT4 glucose transporter proteins
Stimulation of glucose transport by thyroid hormone in 3T3-L1 adipocytes: increased abundance of GLUT1 and GLUT4 glucose transporter proteins
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DOI：
10.1677/joe.0.1640187
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发表时间：
2000-02-01
影响因子：
4
通讯作者：
Rovira, A
中科院分区：
文献类型：
--
作者：
Romero, R;Casanova, B;Rovira, A
在 3T3-L1 脂肪细胞中，我们研究了三碘甲状腺原氨酸 (T-3) 对葡萄糖转运、总蛋白含量以及 GLUT1 和 GLUT4 葡萄糖转运蛋白的亚细胞分布的影响。在 T-3 耗尽的血清中孵育的细胞用作对照。用 T-3 (50 nM) 处理三天的细胞葡萄糖摄取量增加了 3.6 倍 (P
In 3T3-L1 adipocytes we have examined the effect of tri-iodothyronine (T-3) on glucose transport, total protein content and subcellular distribution of GLUT1 and GLUT4 glucose transporters. Cells incubated in T-3-depleted serum were used as controls. Cells treated with T-3 (50 nM) for three days had a 3.6-fold increase in glucose uptake (P