Testing macro-evolutionary models using incomplete molecular phylogenies
Testing macro-evolutionary models using incomplete molecular phylogenies
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DOI：
10.1098/rspb.2000.1278
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发表时间：
2000-11-22
影响因子：
4.7
通讯作者：
Harvey, PH
中科院分区：
文献类型：
--
作者：
Pybus, OG;Harvey, PH
从基因序列重建的系统发育可以用来研究物种多样化的克里思和模式。在这里，我们开发和使用新的统计方法来推断过去的模式的物种形成和灭绝的分子生物学。具体来说，我们测试的零假设，每谱系物种形成和灭绝率一直保持不变，通过时间。拒绝这一假设可能会为进化事件提供证据，如适应性辐射或关键适应。与以前的方法相比，我们的方法是强大的不完整的分类单元采样和灭绝方面是保守的。使用模拟，我们调查，第一，不考虑不完全抽样的不利影响，第二，我们的测试的功率和可靠性。当应用于已发表的物种形成时，我们的测试表明，在某些情况下，物种形成率随着时间的推移而下降。
Phylogenies reconstructed from gene sequences can be used to investigate the tempo and mode of species diversification. Here we develop and use new statistical methods to infer past patterns of speciation and extinction from molecular phylogenies. Specifically, we test the null hypothesis that per-lineage speciation and extinction rates have remained constant through time. Rejection of this hypothesis may provide evidence for evolutionary events such as adaptive radiations or key adaptations. In contrast to previous approaches, our methods are robust to incomplete taxon sampling and are conservative with respect to extinction. Using simulation we investigate, first, the adverse effects of failing to take incomplete sampling into account and, second, the power and reliability of our tests. When applied to published phylogenies our tests suggest that, in some cases, speciation rates have decreased through time.