Severe lead poisoning in the plastics industry: A report of three cases
Severe lead poisoning in the plastics industry: A report of three cases
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DOI：
10.1002/ajim.20123
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发表时间：
2005-02-01
影响因子：
3.5
通讯作者：
Hipkins, K
中科院分区：
文献类型：
--
作者：
Coyle, P;Kosnett, MJ;Hipkins, K
背景铅稳定剂（例如，硫酸铅、硬脂酸铅）是用于电气设备的塑料中的常用添加剂。1997年加州某公司3名塑料厂工人发生严重铅中毒事故，方法通过对工人、雇主、治疗医生的访谈，查阅病历和环境监测结果进行调查。除了测量血铅水平（BLLs），非侵入性K X-射线荧光测量骨铅浓度的索引case.Results诊断时的三名工人的血铅浓度分别为159，114和108，微克/分升。暴露量最高的工人临床表现为痉挛性腹痛、便秘、正常红细胞性贫血、疲劳和可逆性氮质血症。他的胫骨、跟骨和髌骨中的骨铅浓度分别为102、219和182 ppm。结论塑料制品中存在严重的铅超标现象，应引起临床医师的高度重视。(C)2005 Wiley-Liss，Inc.
Background Lead stabilizers (e.g., lead sulfate, lead stearate) are common additives in plastics used in electrical devices. In 1997, three plastics compounders at one California company were severely lead-poisoned.Methods The poisonings were investigated by interviewing the workers, employer and treating physician and reviewing medical records and environmental monitoring results. In addition to measuring blood lead levels (BLLs), noninvasive K X-ray fluorescence was used to measure bone lead concentration of the index case.Results Blood lead concentrations of the three workers at time of diagnosis were 159, 114, and 108,mug/dl. The worker with highest exposure presented with clinical findings of crampy abdominal pain, constipation, normocytic anemia, fatigue, and reversible azotemia. Bone lead concentration in his tibia, calcaneous, and patella were 102, 219, and 182 ppm, respectively. The poisonings resulted from uncontrolled use of powdered lead sulfate stabilizer.Conclusion Clinicians should be aware of potential serious overexposure to lead in compounding of plastics. (C) 2005 Wiley-Liss, Inc.