Psychophysiological correlates of social judgement in high-functioning adults with autism spectrum disorder
Psychophysiological correlates of social judgement in high-functioning adults with autism spectrum disorder
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DOI：
10.1016/j.ijpsycho.2012.11.005
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发表时间：
2013-01-01
影响因子：
3
通讯作者：
Rushby, Jacqueline A.
中科院分区：
文献类型：
--
作者：
Mathersul, Danielle;McDonald, Skye;Rushby, Jacqueline A.
参与社会认知的神经结构（例如杏仁核、眶额皮质）与可信度判断有关。这些区域在自闭症谱系障碍 (ASD) 患者中的功能也非典型。调查自闭症谱系障碍者可信度判断的研究表明，社会刺激的重要性分配可能会受到干扰。考虑到它们在注意力方向和重要性分配中的作用，自主反应的并行测量可以进一步了解这些缺陷。 30 名患有 ASD 的高功能成年人和 31 名非临床对照者将中性图像视为最“积极”和“消极”。记录皮肤电导（SCR、SCL）和诱发心脏减速（ECD）。患有自闭症谱系障碍的成年人在可信度评级方面与对照组没有差异。然而，他们表现出非典型的 SCR，为情感意义分配的破坏提供了进一步的支持。 (C) 2012 Elsevier B.V. 保留所有权利。
Neural structures involved in social cognition (e.g., amygdala, orbitofrontal cortex) have been implicated in judgements of trustworthiness. These regions are also functionally atypical in individuals with autism spectrum disorders (ASDs). Studies investigating judgements of trustworthiness in ASDs have suggested possible disruptions in the allocation of significance to social stimuli. Concurrent measures of autonomic responses provide further insight into these deficits, given their role in the direction of attention and allocation of significance. Thirty high-functioning adults with ASDs and 31 non-clinical controls viewed neutral images piloted as most "positive" and "negative." Skin conductance (SCR, SCL) and evoked cardiac deceleration (ECD) were recorded. Adults with ASDs did not differ from controls in ratings of trustworthiness. However, they displayed atypical SCRs, providing further support for a disruption in the allocation of emotional significance. (C) 2012 Elsevier B.V. All rights reserved.