Effect of renal failure on laudanosine excretion in man.
Effect of renal failure on laudanosine excretion in man.
复制标题
肾衰竭对人劳丹诺辛排泄的影响。
DOI：
10.1093/bja/57.11.1049
复制
发表时间：
1985
影响因子：
9.8
通讯作者：
Hennis,PJ
中科院分区：
文献类型：
--
作者：
Fahey,MR;Rupp,SM;Canfell,C;Fisher,DM;Miller,RD;Sharma,M;Castagnoli,K;Hennis,PJ
Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system stimulant in a variety of animal species, its actions should be investigated further in man, and particularly in patients with renal failure.
