Control of food consumption by learned cues: A forebrain-hypothalamic network
Control of food consumption by learned cues: A forebrain-hypothalamic network
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DOI：
10.1016/j.physbeh.2007.04.014
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发表时间：
2007-07-24
影响因子：
2.9
通讯作者：
Gallagher, Michela
中科院分区：
文献类型：
--
作者：
Petrovich, Gorica D.;Gallagher, Michela
动机在控制食物摄入方面起着重要作用。这篇评论将集中在最近的研究结果，使用神经系统分析的行为模型学习动机控制的饮食。在这个模型中，通过巴甫洛夫条件反射获得动机属性的环境线索随后可以覆盖饱腹感并促进饱腹大鼠的进食。证据将提出，大脑网络形成的杏仁核，外侧下丘脑，内侧前额叶皮层介导这种现象的条件增强的喂养。该动物模型可能有助于理解人类对进食的控制，包括导致暴饮暴食的适应不良影响。(C)2007年爱思唯尔公司All rights reserved.
Motivation plays an important role in the control of food intake. This review will focus on recent findings using a neural systems analysis of a behavioral model for learned motivational control of eating. In this model, environmental cues that acquire motivational properties through Pavlovian conditioning can subsequently override satiety and promote eating in sated rats. Evidence will be presented that a brain network formed by the amygdala, lateral hypothalamus, and medial prefrontal cortex mediates this phenomenon of conditioned potentiation of feeding. The animal model may be informative for understanding control of eating in humans including maladaptive influences that contribute to overeating. (C) 2007 Elsevier Inc. All rights reserved.