Grid infrastructures for secure access to and use of bioinformatics data: experiences from the BRIDGES project
Grid infrastructures for secure access to and use of bioinformatics data: experiences from the BRIDGES project
复制标题
用于安全访问和使用生物信息学数据的网格基础设施：BRIDGES 项目的经验
DOI：
--
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
J. Koetsier
中科院分区：
文献类型：
--
作者：
R. Sinnott;Micha Bayer;A. Stell;J. Koetsier
桥梁项目由英国贸易和工业部(DTI)资助，作为惠康信托资助(#434万)心血管功能基因组学(CFG)项目的一部分，旨在满足研究高血压遗传原因的心血管研究科学家的需求。安全是桥梁项目的核心，一个结合了最新网格授权技术的高级数据和计算网格基础设施被开发并交付给科学家。我们概述了这些网格基础设施，并在项目开始时描述了感知到的安全需求，包括数据分类以及这些需求如何在项目的整个生命周期中发展。还介绍了项目成果的吸收和采用情况，以及为支持生命科学数据集的安全交换而必须克服的挑战。我们还介绍了我们将如何在国家电子科学中心未来的项目中使用这些桥梁的经验。
The BRIDGES project was funded by the UK Department of Trade and Industry (DTI) to address the needs of cardiovascular research scientists investigating the genetic causes of hypertension as part of the Wellcome Trust funded (#4.34M) cardiovascular functional genomics (CFG) project. Security was at the heart of the BRIDGES project and an advanced data and compute grid infrastructure incorporating latest grid authorisation technologies was developed and delivered to the scientists. We outline these grid infrastructures and describe the perceived security requirements at the project start including data classifications and how these evolved throughout the lifetime of the project. The uptake and adoption of the project results are also presented along with the challenges that must be overcome to support the secure exchange of life science data sets. We also present how we will use the BRIDGES experiences in future projects at the National e-Science Centre.