The structures and antibacterial properties of nano-SiO2 supported silver/zinc-silver materials
The structures and antibacterial properties of nano-SiO2 supported silver/zinc-silver materials
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DOI：
10.1016/j.dental.2007.04.015
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发表时间：
2008-02-01
期刊：
影响因子：
5
通讯作者：
Liu Xuguang
中科院分区：
文献类型：
--
作者：
Jia Husheng;Hou Wenshen;Liu Xuguang
目标.研究了两种纳米SiO2抗菌复合材料的结构和抗菌性能。采用吸附法合成样品。其中一种是将银阳离子吸附到纳米SiO2载体上（载银纳米SiO2样品（SLS）），另一种是将锌和银阳离子共吸附到同一种载体上（锌-银-载纳米SiO2样品（SLZS））。对这些样品的化学成分进行了估计。用X射线衍射仪（XRD）和高分辨透射电子显微镜（HRTEM）对样品的结构和形貌进行了表征。同时，对样品的抗菌性能进行了检测。SLZS的载银量与SLS相近。因此，可以证明纳米SiO2吸附银阳离子的量不随锌阳离子的加入而改变。各样品的XRD图谱没有明显差异。因此，可以确认在Ag+/Zn 2+吸收后没有形成新相。高分辨透射电子显微镜（HRTEM）观察到负载的银和锌以纳米粒子的形式存在。SLS和SLZS对大肠杆菌和S.粪便。研究了同一抗菌剂对大肠杆菌的抗菌效果。coli或S.粪便是不同的。此外，SLZS的抑菌效果优于SLS，差异有显著性。这些结果表明SLS和SLZS可以有效地掺入牙科树脂基材料中，以提供对细菌的抗菌活性。(c)2007年由Elsevier Ltd代表牙科材料学会出版。All rights reserved.
Objectives. The aims of this study were to investigate the structures and antibacterial properties of two kinds of sterilizing nano-SiO2 specimens.Methods. The specimens were synthesized by adsorption methodology. one of them was synthesized by adsorbing silver cation onto nano-SiO2 carrier (silver-loading nano-SiO2 specimen (SLS)), and the other one by co-adsorbing zinc and silver cations onto the same kind of carrier (zinc-silver-loading nano-SiO2 specimen (SLZS)). Chemical compositions of these specimens were estimated. The structure and morphology of the specimens were determined by X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM). Also, the antibacterial properties of the specimens were examined.Results. The amount of silver loaded in SLZS was approximate to that of SLS. Consequently, it can be proved that the amount of nano-SiO2 adsorbed silver cation did not change with the addition of zinc cation. The obvious differences were not observed among the XRD patterns for each specimen. So it was possible to confirm no formation of new phase(s) after Ag+/Zn2+ absorption. The loaded silver and zinc existed as nano-particles, as observed by HRTEM. Antibacterial properties of SLS and SLZS were excellent against Escherichia coli and S. faecalis. The antibacterial effect of the same antibacterial agent against E. coli or S. faecalis was different. In addition, the antibacterial effect of SLZS was better than that of SLS.Significance. These results suggested SLS and SLZS can be effectively incorporated in dental resin-based materials to provide antibacterial activity against bacteria. (c) 2007 Published by Elsevier Ltd on behalf of Academy of Dental Materials. All rights reserved.