Identifying the default mode network structure using dynamic causal modeling on resting-state fMRI

Identifying the default mode network structure using dynamic causal modeling on resting-state fMRI
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DOI:
10.7490/f1000research.1093584.1
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发表时间:
2013-07
期刊:
影响因子:
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通讯作者:
X. Di;B. Biswal
X. Di;B. Biswal
中科院分区:
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文献类型:
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作者:
X. Di;B. Biswal

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•分析了来自1000个功能连接体项目的64名受试者的静息状态数据(http://fcon_1000.projects.nitrc.org/)(21名男性,平均年龄21.2岁)5。•每个受试者获得230张图像,TR为2s。扫描参数可以在项目网站上找到。•使用SPM8进行预处理,包括运动校正,通过对解剖图像进行归一化对功能图像进行空间归一化,以及使用8mm高斯核进行空间平滑。•使用GIFT6进行空间独立成分分析来定义DMN。利用傅立叶级数建模低频波动
• Resting-state data of 64 subjects from the 1000 Functional Connectomes Project was analyzed (http://fcon_1000.projects.nitrc.org/) (21 male, mean age 21.2 years)5. • 230 images were acquired for each subject using a TR of 2s. Scanning parameters can be found in the project website. • Preprocessing using SPM8 included motion correction, spatial normalization of the functional images via normalizing the anatomical image, and spatial smoothing using an 8mm Gaussian kernel. • Spatial independent component analysis was conducted to define the DMN using GIFT6. Modeling low-frequency fluctuations using Fourier Series