α-Glucosidase Inhibition Activity by Cyclic Diarylheptanoids from Alnus sieboldiana
α-Glucosidase Inhibition Activity by Cyclic Diarylheptanoids from Alnus sieboldiana
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DOI：
10.1080/02773813.2012.723778
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发表时间：
2013-01-01
影响因子：
2
通讯作者：
Nishida, Tomoaki
中科院分区：
文献类型：
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作者：
Chiba, Koujiro;Ichizawa, Hiroo;Nishida, Tomoaki
从天山赤杨树枝中分离得到一个新化合物，命名为3，17-dihydroxy-tricyclo[12.3.1.1(2，6)]nonadeca-1(18)，2，4，6(19)，14，16-己烯-9，11-二酮，以及两个已知的二芳基庚烷类化合物。根据核磁共振和MS数据，通过一维和二维核磁共振分析，对该化合物的化学结构进行了指认。这三个二芳基庚烷类化合物对-葡萄糖苷酶的活性有明显的抑制作用。
A diarylheptanoid, named 3,17-dihydroxy-tricyclo[12.3.1.1(2,6)]nonadeca- 1(18),2,4,6(19),14,16-hexaen-9,11-dione, was newly isolated from the branch wood of Alnus sieboldiana, together with two known diarylheptanoids. The chemical structure of this compound was assigned on the basis of the NMR and MS data, information obtained though 1D- and 2D-NMR analyses. These three diarylheptanoids were found to significantly inhibit the activity of -glucosidase.