Plasma cells for hire: prior experience required.

Plasma cells for hire: prior experience required.
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出租浆细胞:需要有相关经验。

DOI:
10.1016/j.immuni.2013.07.009
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发表时间:
2013
期刊:
影响因子:
32.4
通讯作者:
Lukin,Kara
Lukin,Kara
中科院分区:
医学1区
文献类型:
--
作者:
Hagman,James;Lukin,Kara

文献摘要

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IgG+记忆B细胞的激活导致了二次免疫应答中的大部分抗体。在这里,Kometani等人。(2013)证明,抗原经历记忆B细胞中Bach 2的量减少控制IgG 1+浆细胞的稳健产生。
Activation of IgG+memory B cells accounts for much of the antibodies in secondary immune responses. Here, Kometani et al. (2013) demonstrate that reduced amounts of Bach2 in antigen-experienced memory B cells control the robust production of IgG1+plasma cells.