Comparison of the effect of multicomponent and resistance training programs on metabolic health parameters in the elderly
Comparison of the effect of multicomponent and resistance training programs on metabolic health parameters in the elderly
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DOI：
10.1016/j.archger.2015.02.005
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发表时间：
2015-05-01
影响因子：
4
通讯作者：
Gibney, Eileen R.
中科院分区：
文献类型：
--
作者：
Leite, Joao Costa;Forte, Roberta;Gibney, Eileen R.
身体活动干预，如阻力训练（RT）和多组分运动训练（MCT），可以改善老年人的功能活动能力，降低残疾风险。关于这种运动是否能有效改善与年龄有关的代谢危险因素的证据较少。本研究旨在比较MCT和RT方案对健康老年人代谢健康参数的影响。方法：21例和18例受试者分别完成了为期12周的MCT和RT计划。干预前后检测体成分、功能能力、有氧适能和代谢健康参数，包括血脂、炎症标志物、葡萄糖代谢、激素和生长标志物。MCT组表皮生长因子循环浓度从35.8 +/- 29.4显著升高至56.1 +/- 35 pg/ml。RT组高分子量脂联素从4.7 +/- 2.9 mg/ml显著降低至4.2 +/- 2.3 mg/ml （p = 0.03）。两组其他生化指标均无明显改变。铁蛋白（p = 0.02）和EGF （p = 0.01）组间差异显著，MCT组铁蛋白浓度降低，RT组升高，MCT组EGF浓度升高，RT组降低。MCT程序改善了功能测试的结果，包括椅子支架和习惯性步行速度。目前的研究结果表明，尽管MCT和RT干预都足以产生功能和身体上的益处，但改善健康老年人的代谢健康需要不同的训练计划和/或运动剂量。2015爱思唯尔爱尔兰有限公司版权所有。
Physical activity interventions such as resistance training (RT) and multicomponent (MCT) exercise training are known to improve functional mobility and reduce the risk of disability among the elderly. Less evidence exists regarding the effectiveness of such exercises to improve metabolic risk factors for age related conditions.This study aimed to compare the effects of MCT and RT programs on metabolic health parameters in healthy elderly.Methods: Twenty one and 18 subjects completed a 12-week MCT and RT program respectively. Before and after intervention, body composition, functional ability, aerobic fitness and metabolic health parameters including lipid profile, inflammatory markers, glucose metabolism, hormones and growth markers were examined.Circulating concentrations of epidermal growth factor increased significantly in the MCT group from 35.8 +/- 29.4 to 56.1 +/- 35 pg/ml. High molecular weight adiponectin decreased significantly in the RT group from 4.7 +/- 2.9 to 4.2 +/- 2.3 mg/ml (p = 0.03). No other biochemical parameter was significantly altered within either group. A significant between group difference was found for both ferritin (p = 0.02) and EGF (p = 0.01), with concentrations of ferritin decreasing in the MCT group and increasing in the RT group and concentration of EGF increasing in the MCT group yet decreasing in the RT group. The MCT program improved results of functional tests including chair stand and habitual walking speed.Present findings suggest that although both the MCT and RT interventions were enough to produce functional and physical benefits, different training programs and/or exercise dose are required to improve metabolic health in healthy older adults. (C) 2015 Elsevier Ireland Ltd. All rights reserved.