Nutrient-rich foods, cardiovascular diseases and all-cause mortality: the Rotterdam study
Nutrient-rich foods, cardiovascular diseases and all-cause mortality: the Rotterdam study
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DOI：
10.1038/ejcn.2014.35
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发表时间：
2014-06-01
影响因子：
4.7
通讯作者：
Feskens, E. J. M.
中科院分区：
文献类型：
--
作者：
Streppel, M. T.;Sluik, D.;Feskens, E. J. M.
背景/目的：富营养食物指数根据食物的营养成分，评定个别食物的营养质素。该指数反映了整体饮食的营养密度。我们研究了NRF9.3指数--一个基于9种有益营养素的分数--（蛋白质，纤维，维生素和矿物质）和三种营养素限制（饱和脂肪、糖和钠）-心血管疾病（CVD）事件的发生率和全因死亡率。共有4969人年龄在55岁及以上的鹿特丹研究，在荷兰的前瞻性队列研究，进行了研究。首先，所有食物都根据其营养成分进行评分，导致食品项目水平的NRF9.3评分。然后，根据受试者摄入的每种食物的卡路里量和总能量摄入量，将其转换为个人加权分数。NRF9.3指数评分的风险比（HR）进行了调整，年龄，性别，体重指数，吸烟史，医生规定的饮食，饮酒和教育。结果：食物组，贡献最大的NRF9.3指数评分是蔬菜，牛奶和奶制品，水果，面包和土豆。高NRF9.3指数评分与全因死亡率呈负相关（HR Q4 vs Q1：0.84（95%置信区间：0.74，0.96））。妇女的联想比男子强。NRF9.3指数评分与CVD发生率无关。结论：NRF9.3指数评分较高的老年人，表明更多的有益成分和/或较少的限制成分，有较低的全因死亡率的风险。营养丰富的饮食可以提高生存率。
BACKGROUND/OBJECTIVES: The nutrient-rich food (NRF) index assesses nutrient quality of individual food items by ranking them according to their nutrient composition. The index reflects the nutrient density of the overall diet. We examined the associations between the NRF9.3 index-a score on the basis of nine beneficial nutrients (protein, fiber, vitamins and minerals) and three nutrients to limit (saturated fat, sugar and sodium)-incidence of cardiovascular disease (CVD) events and all-cause mortality.SUBJECTS/METHODS: A total of 4969 persons aged 55 and older from the Rotterdam Study, a prospective cohort study in the Netherlands, were studied. First, all foods were scored on the basis of their nutrient composition, resulting in an NRF9.3 score on food item level. Subsequently, they were converted into individual weighted scores on the basis of the amount of calories of each food item consumed by the subjects and the total energy intake. The hazard ratios (HRs) of the NRF9.3 index score were adjusted for age, gender, body mass index, smoking history, doctor-prescribed diet, alcohol consumption and education.RESULTS: Food groups that contributed most to the NRF9.3 index score were vegetables, milk and milk products, fruit, bread and potatoes. A high NRF9.3 index score was inversely associated with all-cause mortality (HR Q4 versus Q1: 0.84 (95% confidence interval: 0.74, 0.96)). Associations were stronger in women than in men. The NRF9.3 index score was not associated with incidence of CVD. CONCLUSION: Elderly with a higher NRF9.3 index score, indicating more beneficial components and/or less limiting components, had a lower risk of all-cause mortality. Consuming a nutrient-dense diet may improve survival.