PARAVENTRICULAR NUCLEUS NEURONS PROJECTING TO THE SPINAL-CORD RECEIVE EXCITATORY INPUT FROM THE SUBFORNICAL ORGAN
PARAVENTRICULAR NUCLEUS NEURONS PROJECTING TO THE SPINAL-CORD RECEIVE EXCITATORY INPUT FROM THE SUBFORNICAL ORGAN
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DOI：
10.1152/ajpregu.1995.268.3.r625
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发表时间：
1995-03-01
影响因子：
2.8
通讯作者：
FERGUSON, AV
中科院分区：
文献类型：
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作者：
BAINS, JS;FERGUSON, AV
本研究利用电生理学技术来确定穹窿下器官 (SFO) 刺激对投射到脊髓的室旁核 (PVN) 神经元活动的影响。单单元记录是从 79 个 PVN 神经元获得的，逆向识别为投射到中间外侧细胞柱 (IML)。逆向诱发动作电位显示平均潜伏期为 94.6 +/- 5.3 ms，平均激活阈值为 1.58 +/- 0.11 mA。 SFO 的电刺激（100 mu A-1.5 mA，0.1 ms）导致测试的 27 个神经元中有 18 个（67%）产生兴奋反应。对此类效应的周刺激直方图分析表明，持续时间为
The present study utilized electrophysiological techniques to determine the effects of subfornical organ (SFO) stimulation on the activity of neurons in the paraventricular nucleus (PVN) projecting to the spinal cord. Single-unit recordings were obtained from 79 PVN neurons antidromically identified as projecting to the intermediolateral cell column (IML). Antidromically evoked action potentials showed a mean latency of 94.6 +/- 5.3 ms and a mean threshold for activation of 1.58 +/- 0.11 mA. Electrical stimulation of SFO (100 mu A-1.5 mA, 0.1 ms) resulted in excitatory responses in 18 of the 27 neurons tested (67%). Peristimulus histogram analysis of such effects demonstrated a duration of