Biologic effects of stress and bonding in mother-infant pairs.
Biologic effects of stress and bonding in mother-infant pairs.
复制标题
压力和粘结在母亲对中的生物学效应。
DOI：
10.1177/0091217416652382
复制
发表时间：
2016-04
影响因子：
2
通讯作者：
Wagner C
中科院分区：
文献类型：
--
作者：
Spratt EG;Marsh C;Wahlquist AE;Papa CE;Nietert PJ;Brady KT;Herbert TL;Wagner C
Maternal stress in humans influences behavior of children and can be assessed using biological markers. Mothers and their one-month-old infants were recruited from an existing study to examine baseline maternal serum oxytocin and hypothalamic-pituitary-adrenal (HPA) axis response to infant blood heel stick stress as measured by salivary cortisol in the dyads. Objectives were to explore (1) relationships between mother and infant cortisol levels, (2) gender differences in infant biologic cortisol response, and (3) the association of cortisol levels in the dyads and maternal oxytocin levels. Forty-two mother-infant dyads provided biologic samples and self-report data. Initial salivary cortisol was assessed in both the mother and infant, followed by a heel stick blood draw. Twenty minutes later, salivary cortisol was collected again from dyads. Self-report measures were negative for depression and risk for childhood neglect. Although oxytocin and baseline cortisol in the infants was higher in mothers that did some breast feeding, there was no statistically significant difference (p=0.2; p=0.1, respectively). Analyses showed (a) higher baseline cortisol in mothers was related to higher baseline cortisol in infants (p<0.0001), (b) following the stressor, female infants had a larger positive change in cortisol, after adjusting for baseline cortisol (p=0.045), and (c) there was no relationship between dyad cortisol levels and maternal oxytocin. Maternal and infant biologic stress measures are related. Female infants have a larger HPA response to a blood draw stressor as measured by salivary cortisol than male infants.
