Predicting full-length transcripts.
Predicting full-length transcripts.
复制标题
预测全长转录本。
DOI:
10.1016/s0167-7799(02)01976-5
复制
发表时间:
2002
影响因子:
17.3
通讯作者:
Brent,MichaelR
中科院分区:
文献类型:
--
作者:
Brent,MichaelR
Accurate prediction of the complete structures of protein-coding genes, including 5′-untranslated regions, is crucial for full interpretation of genome sequence. A new report describes the statistical properties of the first exons of genes, and presents a novel statistical method for predicting their boundaries. First exons, which are partially or completely non-coding, have been relatively neglected by gene-finding algorithms. When integrated with other genome annotation tools, this new method will improve the technology of automated genome interpretation.