Interference of functional monomers with polymerization efficiency of adhesives
Interference of functional monomers with polymerization efficiency of adhesives
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DOI：
10.1111/eos.12245
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发表时间：
2016-04-01
影响因子：
1.9
通讯作者：
Van Meerbeek, Bart
中科院分区：
文献类型：
--
作者：
Hanabusa, Masao;Yoshihara, Kumiko;Van Meerbeek, Bart
樟脑酚/胺基胶粘剂的转化率(DC)受酸性官能团单体的影响，因为胺类共引发剂通过酸碱反应失活。在粘接过程中，自酸蚀粘结剂的功能单体与羟基磷灰石(HAP)发生化学作用。在这里，我们测试了功能单体与HAP的后一种相互作用在多大程度上抵消了樟脑醌/胺类粘合剂预期的DC降低。在粘合剂配方中加入和不加入羟基磷灰石粉末，测量了三种实验胶粘剂配方中含有两种功能单体之一[10-甲基丙烯酰氧基十烷基磷酸二氢(10-MDP)或4-甲基丙烯酰氧乙基偏苯三酸酐(4-META)]或不含功能单体(NO-FM；对照)的DC。两个变量的功能单体‘和HAP’被发现是显著的，功能单体降低DC和HAP抵消了这一影响。结果表明，功能单体10-MDP和4-META对胶粘剂的聚合效率有干扰作用。这种干扰在HAP存在时不那么明显，这在临床上相当于粘合剂的这两个功能单体同时与牙齿组织中的HAP相互作用。
The degree of conversion (DC) of camphorquinone/amine-based adhesives is affected by acidic functional monomers as a result of inactivation of the amine co-initiator through an acid-base reaction. During bonding, functional monomers of self-etch adhesives chemically interact with hydroxyapatite (HAp). Here, we tested in how far the latter interaction of functional monomers with HAp counteracts the expected reduction in DC of camphorquinone/amine-based adhesives. The DC of three experimental adhesive formulations, containing either of the two functional monomers [10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) or 4-methacryloxyethyl trimellitic acid anhydride (4-META)] or no functional monomer (no-FM; control), was measured with and without HAp powder added to the adhesive formulations. Both the variables functional monomer' and HAp' were found to be significant, with the functional monomer reducing the DC and HAp counteracting this effect. It is concluded that the functional monomers 10-MDP and 4-META interfere with the polymerization efficiency of adhesives. This interference is less prominent in the presence of HAp, which would clinically correspond to when these two functional monomers of the adhesive simultaneously interact with HAp in tooth tissue.