Effect of colour of drugs: Systematic review of perceived effect of drugs and of their effectiveness
Effect of colour of drugs: Systematic review of perceived effect of drugs and of their effectiveness
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DOI：
10.1136/bmj.313.7072.1624
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发表时间：
1996-12-21
影响因子：
--
通讯作者：
Kleijnen, J
中科院分区：
文献类型：
--
作者：
deCraen, AJM;Roos, PJ;Kleijnen, J
Objectives-To assess the impact of the colour of a drug's formulation on its perceived effect and its effectiveness and to examine whether the antidepressant drugs available in the Netherlands are different in colour from hypnotic，sedative，and anxiolytic drugs. Design-Systematic review of 12 published studies，Six studies examined the perceived action of different colour drugs and six the impact of the colour of a drug on its effectiveness.用彩色图谱对49种影响中枢神经系统的药物样品的颜色进行了评价，主要结果指标：药物颜色的兴奋作用与兴奋作用;在患有不同疾病的患者中进行了评估不同颜色药物效果的试验，并具有不同的结果测量。结果-对有色药物感知作用的研究表明，红色，黄色，橙子与兴奋作用有关，而蓝色和绿色与镇静作用有关。评估药物颜色对其有效性影响的试验显示，颜色之间的差异不一致。这些试验方法的质量各不相同。催眠药，镇静药，抗焦虑药比抗抑郁药更有可能是绿色，蓝色，或purple. Conclusion颜色影响药物的感知作用，似乎影响药物的有效性。此外，影响中枢神经系统的药物的颜色与其使用的适应症之间存在关系。有必要进行有助于更好地了解药物颜色影响的研究。
Objectives-To assess the impact of the colour of a drug's formulation on its perceived effect and its effectiveness and to examine whether antidepressant drugs available in the Netherlands are different in colour fi om hypnotic, sedative, and anxiolytic drugs.Design-Systematic review of 12 published studies, Six studies examined the perceived action of different coloured drugs and six the influence of the colour of a drug on its effectiveness. The colours of samples of 49 drugs affecting the central nervous system were assessed using a colour atlas.Main outcome measures-Perceived stimulant action versus perceived depressant action of colour of drugs; the trials that assessed the effect of drugs in different colours were done in patients with different diseases and had different outcome measures.Results-The studies on perceived action of coloured drugs showed that red, yellow, and orange are associated with a stimulant effect, while blue and green are related to a tranquillising effect. The trials that assessed the impact of the colour of drugs on their effectiveness showed inconsistent differences between colours. The quality of the methods of these trials was variable. Hypnotic, sedative, and anxiolytic drugs were more likely than antidepressants to be green, blue, or purple.Conclusion-Colours affect the perceived action of a drug and seem to influence the effectiveness of a drug. Moreover, a relation exists between the colouring of drugs that affect the central nervous system and the indications for which they are used. Research contributing to a better understanding of the effect of the colour of drugs is warranted.