Comparison of the effects of compression plates and external fixators on early bone-healing.
Comparison of the effects of compression plates and external fixators on early bone-healing.
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DOI：
10.2106/00004623-198466070-00016
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发表时间：
1984-09
期刊：
影响因子：
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通讯作者：
D. Lewallen;E. Chao;R. Kasman;P. Kelly
中科院分区：
文献类型：
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作者：
D. Lewallen;E. Chao;R. Kasman;P. Kelly
在标准犬截骨模型中，我们使用了两种机械上不同的装置，加压骨板和单侧框架外固定架；两种方法在实现成熟骨愈合方面都非常成功。采用组织学、生理学和生物力学方法研究骨愈合。损伤后120天，外固定架侧愈合生物力学不成熟。这些胫骨皮质内新骨形成较少（p < 0.01），骨吸收较多（p < 0.045），骨孔隙率较高（p < 0.04）。外固定架侧较高水平的骨转换伴随着血流量的增加（通过85Sr清除率测量）（p < 0.04）。在截骨部位，外固定架一侧实验前或未标记的骨和孔隙度较大，钢板侧骨内新生骨形成较大。由于除了侧弯外，外固定架的体外刚度在所有测试模式（压缩、牵张、扭转和前后弯曲）中都较低，因此固定架的刚度可能是愈合性截骨术后早期骨重塑的重要因素。
We used two mechanically dissimilar devices, compression bone-plates and unilateral-frame external fixators, in a standard canine osteotomy model; both methods were highly successful in achieving mature bone union. Bone union was studied by histological, physiological, and biomechanical means. At 120 days after injury, union was biomechanically less mature on the external fixator side. These tibiae had less intracortical new-bone formation (p less than 0.01), more bone resorption (p less than 0.045), and more bone porosity (p less than 0.04) when compared with paired tibiae that had been treated with compression plates. This higher level of bone turnover on the external fixator side was accompanied by an increase in blood flow (measured by clearance of 85Sr) (p less than 0.04). At the osteotomy site, pre-experimental or unlabeled bone and porosity were greater on the external fixator side and endosteal new-bone formation was greater on the plated side. Since the in vitro stiffness of the external fixator was less in all modes tested (compression, distraction, torsion, and anteroposterior bending) except lateral bending, it may be that the rigidity of the fixation is an important factor in early bone-remodeling of a healing osteotomy.