Effect of varicocelectomy on the plasma oxidative stress parameters
Effect of varicocelectomy on the plasma oxidative stress parameters
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DOI：
10.1016/j.jpedsurg.2005.11.018
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发表时间：
2006-02-01
影响因子：
2.4
通讯作者：
Ottolenghi, A
中科院分区：
文献类型：
--
作者：
Cervellione, RM;Cervato, G;Ottolenghi, A
研究目的：本研究通过血浆氧化应激参数来评估精索静脉曲张切除术的长期效果。方法：11 名 10 至 16 岁儿童患有左侧精索静脉曲张和同侧睾丸发育不全。术前和精索静脉曲张切除术后 1 年采集外周血样本，检测 C 反应蛋白、基础硫代巴比妥酸反应物质 (TBARS) 和血浆过氧化敏感性（滞后时间和斜率）。所有患者均接受腹股沟微血管精索静脉曲张切除术和睾丸-下腹（精索-上腹）静脉分流术，并从绒毛神经丛采集血样。使用学生 I 检验未配对和配对数据，显着性水平设置为 P
Aim of Study: This study evaluates the long-term effect of varicocelectomy as measured by plasma oxidative stress parameters.Methods: Eleven children aged 10 to 16 years presented with left-sided varicocele and ipsilateral testicular hypoplasia. Peripheral blood samples for C-reactive protein, basal thiobarbituric acid reactive substances (TBARS), and plasma peroxidation susceptibility (lag time and slope) were obtained preoperatively and at 1 year after the varicocelectomy. All patients underwent inguinal microvascular varicocclectomy with testicular-inferior epigastric (spermatic-epigastric) venous shunt, and a blood sample from the pampinous plexus was taken. Student's I test for Unpaired and paired data was used with a level of significance set at P