Effect of patient characteristics on reported outcomes after total knee replacement
Effect of patient characteristics on reported outcomes after total knee replacement
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DOI：
10.1093/rheumatology/kel184
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发表时间：
2007-01-01
期刊：
影响因子：
5.5
通讯作者：
Gutierrez, L. F.
中科院分区：
文献类型：
--
作者：
Escobar, A.;Quintana, J. M.;Gutierrez, L. F.
客观的。评估预干预因素对全膝关节置换术后 6 个月患者报告结果的影响。方法。一项前瞻性观察研究是在患者等待手术时发送给患者的两份调查问卷进行的：一份通用调查问卷，即医疗结果研究简表-36 (SF-36)，以及一份特定调查问卷，即西安大略大学和麦克马斯特大学骨关节炎指数 (WOMAC)。干预六个月后，患者再次收到相同的问卷。因变量是 WOMAC 的三个域和 SF-36 的八个域的分数。结果。我们招募了 640 名患者。平均年龄为 71 岁，73.6% 的患者为女性。多变量分析（其中将每个领域的干预前得分作为协变量添加）表明，最显着的干预前预测因素是每个领域的基线得分。除此之外，社会支持、腰痛和心理健康领域的基线评分 (SF-36) 是三个 WOMAC 领域的干预前预测因素。关于 SF-36 领域，主要预测因素是基线心理健康评分、合并症、腰痛和社会支持。结论。所有 11 个领域术后 6 个月结果的主要预测因素是每个领域的干预前评分。社会支持的存在、腰痛的消失和较高的基线 SF-36 心理健康评分与术后健康相关生活质量的改善有关。
Objective. To evaluate the effect of pre-intervention factors in patient-reported outcomes at 6 months post-operatively following total knee replacement.Methods. A prospective observational study was carried out using two questionnaires sent to patients while they were on the waiting list for surgery: a generic questionnaire, the Medical Outcomes Study Short Form-36 (SF-36), and a specific questionnaire, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Six months after intervention, patients again received the same questionnaires. The dependent variables were the scores of the three domains of the WOMAC and the eight domains of the SF-36.Results. We recruited 640 patients. The mean age was 71 yrs and 73.6% of the patients were females. The multivariate analysis, in which the pre-intervention scores for each domain were added as covariates, showed that the most significant pre-intervention predictors were the baseline scores of each domain. Besides that, the social support, low back pain and the baseline score of the mental health domain (SF-36) were the pre-intervention predictors in the three WOMAC domains. With regard to the SF-36 domains the main predictors were the baseline mental health score, comorbidities, low back pain and social support.Conclusions. The main predictor of outcome at 6 months post-operatively in all eleven domains was the pre-intervention score of each domain. Presence of social support, absence of low back pain and higher baseline SF-36 mental health score were related to the improvement in the health-related quality of life post-operatively.