OBSERVATIONS ON THE EFFECTS OF THE H-52 AND H-120 VACCINE STRAINS OF INFECTIOUS BRONCHITIS VIRUS IN THE DOMESTIC FOWL
OBSERVATIONS ON THE EFFECTS OF THE H-52 AND H-120 VACCINE STRAINS OF INFECTIOUS BRONCHITIS VIRUS IN THE DOMESTIC FOWL
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DOI：
10.1080/03079457608418182
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发表时间：
1976-01-01
期刊：
影响因子：
2.8
通讯作者：
MCMARTIN D A
中科院分区：
文献类型：
--
作者：
MACDONALD J W;MCMARTIN D A
比较了H120和H52传染性支气管炎疫苗病毒对1日龄和12周龄雏鸡的致病性。两种病毒均产生中度呼吸道症状。两者也都是嗜肾性的，但H52伴随着肉眼和显微镜下的肾脏变化，这可能是导致死亡的原因，而H120在肾脏中没有变化，也没有死亡。这两种病毒引起的法氏囊的肉眼和显微镜下的变化。
The pathogenicity of H120 and H52 infectious bronchitis vaccine viruses was compared in 1-day-old 12-wk-old chickens. Both viruses produced moderate respiratory symptoms. Both were also nephrotropic, but whereas H52 was accompanied by gross and microscopic kidney changes, which probably accounted for the mortality which occurred, H120 produced no change in the kidney and no mortality. Both viruses caused gross and microscopic changes in the bursa of Fabricius.