Lower gastrointestinal tract dysfunction in patients receiving long-term hemodialysis.
Lower gastrointestinal tract dysfunction in patients receiving long-term hemodialysis.
复制标题
长期血液透析患者的下消化道功能障碍。
DOI：
10.1001/archinte.1982.00340150103019
复制
发表时间：
1982
影响因子：
--
通讯作者：
S. Y. Han
中科院分区：
文献类型：
--
作者：
P. Adams;E. Rutsky;S. Rostand;S. Y. Han
在10年期间接受长期血液透析的945名患者中，有25名出现了严重的肠功能障碍。发生结肠穿孔12例，其中6例死于腹膜炎。在7例中，穿孔是自发的。另有10名患者表现为长期严重的动态肠梗阻，在8名患者中发展为结肠假性梗阻。内科减压术(8例)和外科肠道减压术(2例)治愈9例。所有患者定期服用的氢氧化铝凝胶，在78%的患者出现肠穿孔或持续性动态肠梗阻之前，与显著的慢性便秘有关。
Severe bowel dysfunction developed in 25 of 945 patients receiving long-term hemodialysis during a ten-year period. Colonic perforation occurred in 12 patients, six of whom died due to peritonitis. In seven instances, the perforation occurred spontaneously. Ten other individuals exhibited prolonged, severe adynamic ileus that progressed to colonic pseudo-obstruction in eight patients. Medical decompression (eight patients) and surgical bowel decompression (two patients) resulted in recovery in nine. Aluminum hydroxide gel, which was taken regularly by all patients, was associated with notable chronic constipation prior to the occurrence of bowel perforation or protracted adynamic ileus in 78% of these individuals.