Embedded template-assisted fabrication of complex microchannels in PDMS and design of a microfluidic adhesive
Embedded template-assisted fabrication of complex microchannels in PDMS and design of a microfluidic adhesive
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DOI：
10.1021/la062516n
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发表时间：
2006-11-21
期刊：
影响因子：
3.9
通讯作者：
Ghatak, Animangsu
中科院分区：
文献类型：
--
作者：
Verma, Mohan K. S.;Majumder, Abhijit;Ghatak, Animangsu
在本文中，我们描述了一种新的方法，用于制造二维和三维微通道图案的柔性平台的交联聚二甲基硅氧烷（PDMS）。在这里，形成不同的二维和三维形状的细长尼龙线被用作嵌入交联PDMS块内的模板。然后使交联的网络在合适的溶剂中溶胀，该溶剂选择性地溶胀网络，但使尼龙线保持不变。然后将线从溶胀的网络中轻轻移除，留下微通道。使用这种简单的方法可以生成各种拓扑复杂取向的通道，如结、螺旋、超螺旋和各种横截面的通道。最后，我们提出了一个应用程序，通过产生内部层的粘合剂在这些微通道，观察到显着提高粘合强度。
In this paper, we describe a novel method for fabricating 2-D and 3-D microchannel patterns in a flexible platform of cross-linked poly(dimethylsiloxane) (PDMS). Here, a slender nylon thread formed into different 2-D and 3-D shapes is used as a template that is embedded inside a block of cross-linked PDMS. The cross-linked network is then allowed to swell in a suitable solvent that swells the network selectively but leaves the nylon thread unaltered. The thread is then gently removed from the swollen network leaving behind a microchannel. Channels of a variety of topologically complex orientations like knots, helices, super-helices, and channels of a variety of cross-sections can be generated using this simple method. Finally, we have presented an application by generating inside layers of adhesive in these microchannels, which are observed to enhance the adhesion strength significantly.