Heart failure with preserved left ventricular Systolic function - Epidemiology clinical characteristics and prognosis

Heart failure with preserved left ventricular Systolic function - Epidemiology clinical characteristics and prognosis
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DOI:
10.1016/j.jacc.2003.07.046
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发表时间:
2004-02-04
影响因子:
24
通讯作者:
McMurray, J
McMurray, J
中科院分区:
医学1区
文献类型:
--
作者:
Hogg, K;Swedberg, K;McMurray, J

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最近的横断面,基于人群的超声心动图研究表明,大约一半的心力衰竭患者保留了左心室收缩功能(HF-PSF)。住院患者的队列研究显示HF-PSF的比例较小。与收缩功能降低的患者相比,HF-PSF患者更常见于女性、老年人,不太可能患有冠状动脉疾病,更可能患有高血压。HF-PSF患者的症状较轻,与收缩功能降低的患者相比,接受不同的药物治疗。HF-PSF患者的发病率和死亡率较高,但不像收缩功能降低的患者那么高。虽然最近对HF-PSF综合征有了很多了解,但仍有许多问题有待回答,尤其是应该如何治疗。(C)2004年,美国心脏病学会基金会。
Recent cross-sectional, population-based echocardiographic studies show that about half of all patients with heart failure have preserved left ventricular systolic function (HF-PSF). Cohort studies of hospitalized patients show a smaller proportion of HF-PSF. Compared to those with reduced systolic function, patients with HF-PSF are more often female, older, less likely to have coronary artery disease, and more likely to have hypertension. Patients with HF-PSF are less symptomatic and receive different pharmacologic therapy than patients with reduced systolic function. Morbidity and mortality rates in patients with HF-PSF are high but not quite as high as in patients with reduced systolic function. Though much has recently been learned about the syndrome of HF-PSF, many questions remain to be answered, not least how it should be treated. (C) 2004 by the American College of Cardiology Foundation.