Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking.
Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking.
复制标题
DOI:
10.3390/v6072899
复制
发表时间:
2014-07-23
期刊:
影响因子:
--
通讯作者:
Abrahamyan L
中科院分区:
文献类型:
--
作者:
Bilkova E;Forstova J;Abrahamyan L
To get access to the replication site, small non-enveloped DNA viruses have to cross the cell membrane using a limited number of capsid proteins, which also protect the viral genome in the extracellular environment. Most of DNA viruses have to reach the nucleus to replicate. The capsid proteins involved in transmembrane penetration are exposed or released during endosomal trafficking of the virus. Subsequently, the conserved domains of capsid proteins interact with cellular membranes and ensure their efficient permeabilization. This review summarizes our current knowledge concerning the role of capsid proteins of small non-enveloped DNA viruses in intracellular membrane perturbation in the early stages of infection.
登录
查看更多内容
影响因子:
30.3
作者:
Bremner KH;Scherer J;Yi J;Vershinin M;Gross SP;Vallee RB
通讯作者:
Vallee RB
影响因子:
3.4
作者:
BAKER, TS;NEWCOMB, WW;BROWN, JC
通讯作者:
BROWN, JC
影响因子:
30.3
作者:
Burckhardt, Christoph J.;Suomalainen, Maarit;Greber, Urs F.
通讯作者:
Greber, Urs F.
影响因子:
4.8
作者:
Benevento, Marco;Di Palma, Serena;Heck, Albert J. R.
通讯作者:
Heck, Albert J. R.
DOI:
10.1038/sj.mt.6300053
发表时间:
2007-03
期刊:
Molecular therapy : the journal of the American Society of Gene Therapy
影响因子:
--
作者:
Akache B;Grimm D;Shen X;Fuess S;Yant SR;Glazer DS;Park J;Kay MA
通讯作者:
Kay MA