ANEMIA VS IRON-DEFICIENCY - INCREASED RISK OF PRETERM DELIVERY IN A PROSPECTIVE-STUDY
ANEMIA VS IRON-DEFICIENCY - INCREASED RISK OF PRETERM DELIVERY IN A PROSPECTIVE-STUDY
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DOI：
10.1093/ajcn/55.5.985
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发表时间：
1992-05-01
影响因子：
7.1
通讯作者：
SHEARER, JW
中科院分区：
文献类型：
--
作者：
SCHOLL, TO;HEDIGER, ML;SHEARER, JW
使用疾病控制中心的标准，在> 800名内城孕妇进入产前护理时评估了贫血和缺铁性贫血（血清铁蛋白浓度< 12 μ g/L的贫血）。缺铁性贫血与妊娠早期能量和铁摄入量显著降低以及平均红细胞体积降低有关。缺铁导致低出生体重的几率增加了两倍，早产的几率增加了一倍多，但其他原因引起的贫血并没有增加。当入院时或入院前阴道出血伴有贫血时，缺铁性贫血早产的几率增加5倍，其他贫血早产的几率增加1倍。妊娠期体重增加不足在缺铁性贫血和其他病因的贫血患者中更为普遍。然而，对于大多数贫血在临床上归因于缺铁的市中心少数民族人群，缺铁性贫血的患病率（3.5%）低于预期。
Using criteria from the Centers for Disease Control, anemia and iron-deficiency anemia (anemia with serum ferritin concentrations < 12-mu-g/L) were assessed in > 800 inner-city gravidas at entry to prenatal care. Iron-deficiency anemia was associated with significantly lower energy and iron intakes early in pregnancy and a lower mean corpuscular volume. The odds of low birth weight were tripled and of preterm delivery more than doubled with iron deficiency, but were not increased with anemia from other causes. When vaginal bleeding at or before entry to care accompanied anemia, the odds of a preterm delivery were increased fivefold for iron-deficiency anemia and doubled for other anemias. Inadequate pregnancy weight gain was more prevalent among those with iron-deficiency anemia and in those with anemias of other etiologies. The prevalence of iron-deficiency anemia (3.5%), however, was lower than anticipated for an inner-city, minority population in whom most anemias had been attributed clinically to iron deficiency.