The Effect of Bovine Bone Graft With or Without Platelet-Rich Plasma on Maxillary Sinus Floor Augmentation
The Effect of Bovine Bone Graft With or Without Platelet-Rich Plasma on Maxillary Sinus Floor Augmentation
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DOI：
10.1016/j.joms.2011.03.040
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发表时间：
2011-10-01
影响因子：
1.9
通讯作者：
Sencift, Kemal
中科院分区：
文献类型：
--
作者：
Cabbar, Fatih;Guler, Nurhan;Sencift, Kemal
目的：本研究的目的是比较Unilab Surgibone（USB）（密西索加，安大略，加拿大），骨异种移植（牛），富血小板血浆（PRP）和USB没有PRP，以增加人上颌窦准备接受牙科种植体。一侧的鼻窦用USB-PRP组合增强并形成研究组，而对侧的鼻窦仅用USB增强并作为对照。在上颌窦底提升后6.8 +/- 0.9个月时，在种植体植入过程中采集骨活检标本。共振频率分析测量进行种植体放置（第一个控制）和修复阶段（第二个控制）之前，在6.5 +/- 0.7个月后种植体surgery.Results：有10例患者（7男3女，平均年龄53.7 +/- 0.8岁）。在所有样本中均观察到新骨和残余移植物之间的整合。对照组和研究组的软组织体积分别为59.9% +/- 7.5%和57.8% +/- 4.4%;残余移植物分别为21.9% +/- 6.6%和23.6% +/-5.9%;新骨分别为15.8% +/- 4.8%和16.0% +/-3.8%;和松质骨，分别为64.7% ± 22.5%和69.1% ± 18.6%。发现新骨体积和松质骨体积之间呈正相关（P = .0001）。对照组和研究组的平均植入物稳定性商（ISQ）值分别为71.7 +/- 4.9和70.3 +/- 5.7（第一次对照）和75.4 +/- 6.4和74.4 +/- 6.4（第二次对照）。两组第二次对照的平均ISQ值均显著高于第一次对照（分别为P = .043和P = .028）。结论：USB和PRP联合应用对种植体的稳定性和新骨形成无明显影响。(C)2011年美国口腔颌面外科医师协会J Oral Mcaillofac Surg 692537-2547，2011年
Purpose: The purpose of this study was to compare Unilab Surgibone (USB) (Mississauga, Ontario, Canada), a bone xenograft (bovine), with platelet-rich plasma (PRP) and USB without PRP to augment the human maxillary sinus in preparation to receive dental implants.Patients and Methods: Patients who had bilateral pneumatized maxillary sinuses were included. Sinuses on one side were augmented with the USB-PRP combination and formed the study group, whereas the opposite-side sinuses were augmented with USB alone and served as controls. Bone biopsy specimens were taken during implant placement at 6.8 +/- 0.9 months after maxillary sinus floor augmentation. Resonance frequency analysis measurements were performed at implant placement (first control) and before the prosthetic stage (second control), at 6.5 +/- 0.7 months after implant surgery.Results: There were 10 patients (7 men and 3 women; mean age, 53.7 +/- 0.8 years). Integration between new bone and residual grafts was histologically observed in all samples. The volumes of soft tissue were 59.9% +/- 7.5% and 57.8% +/- 4.4% in the control and study groups, respectively; residual graft, 21.9% +/- 6.6% and 23.6% +/- 5.9%, respectively; new bone, 15.8% +/- 4.8% and 16.0% +/- 3.8%, respectively; and trabecular bone, 64.7% +/- 22.5% and 69.1% +/- 18.6%, respectively. A positive correlation was found between new bone volume and trabecular bone volume (P = .0001). The mean Implant Stability Quotient (ISQ) values were 71.7 +/- 4.9 and 70.3 +/- 5.7 in the control and study groups, respectively, at first control and 75.4 +/- 6.4 and 74.4 +/- 6.4, respectively, at second control. The mean ISQ values at second control in both groups were significantly higher than at first control (P = .043 and P = .028, respectively). No statistically significant differences were observed between groups (P > .05).Conclusion: The combination of USB and PRP does not have any effect on new bone formation and implant stabilization. (C) 2011 American Association of Oral and Maxillofacial Surgeons J Oral Mcaillofac Surg 692537-2547, 2011