EPITHELIOID HAEMANGIOMA-LIKE VASCULAR PROLIFERATION IN AIDS: MANIFESTATION OF CAT SCRATCH DISEASE BACILLUS INFECTION?
EPITHELIOID HAEMANGIOMA-LIKE VASCULAR PROLIFERATION IN AIDS: MANIFESTATION OF CAT SCRATCH DISEASE BACILLUS INFECTION?
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艾滋病中的上皮样血管瘤样血管增殖：猫抓病芽孢杆菌感染的表现？
DOI：
10.1016/s0140-6736(88)91779-5
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
D. Wear
中科院分区：
文献类型：
--
作者：
P. Leboit;B. Egbert;M. Stoler;J. Strauchen;T. Berger;T. Yen;T. Bonfiglio;C. English;D. Wear
7例获得性免疫缺陷综合征患者的丘疹和结节性皮肤病变在临床上类似于卡波西肉瘤，但在组织学上表现为明显的上皮样血管瘤样外观。在每个血管增生中通过电子显微镜鉴定出具有革兰氏阴性棒结构的细菌簇。细菌没有用布朗布伦染色，抗酸染色，或其他组织化学染色染色的感染性生物，但用华氏染色，即染色谱描述的猫抓病（CSD）芽孢杆菌。免疫过氧化物酶染色，使用兔培养的抗血清对抗培养的CSD杆菌，在所有五个测试病例中显示出与细菌的阳性反应。两名幸存的患者都有被猫抓伤的病史。在一些患者中，血管病变在使用适合于CSD杆菌感染的抗生素治疗后消退。
Papular and nodular skin lesions that clinically resembled Kaposi sarcoma, but histologically showed a distinct epithelioid haemangioma-like appearance, were noted in seven patients with the acquired immunodeficiency syndrome. Clusters of bacteria that had the structure of gram-negative rods were identified within each of the vascular proliferations by electron microscopy. The bacteria did not stain with the Brown-Brenn, acid-fast, or other histochemical stains for infectious organisms, but did stain with Warthin-Starry—ie, the staining profile was that described for the cat scratch disease (CSD) bacillus. Immunoperoxidase staining, using antisera raised in rabbits against cultured CSD bacillus, showed a positive reaction with the bacterium in all five cases tested. The two surviving patients have both given histories of having been scratched by a cat. In several patients, the vascular lesions regressed after therapy with antibiotics appropriate for CSD bacillus infection.
帕里诺眼腺综合征患者结膜中的猫抓病杆菌。
影响因子：
13.7
作者：
Wear,DJ;Malaty,RH;Zimmerman,LE;Hadfield,TL;Margileth,AM
通讯作者：
Margileth,AM