Outpatient management of alcohol-related liver disease.
Outpatient management of alcohol-related liver disease.
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DOI：
10.1016/s2468-1253(19)30415-7
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发表时间：
2020-05
期刊：
影响因子：
--
通讯作者：
Kamath PS
中科院分区：
文献类型：
--
作者：
Simonetto DA;Shah VH;Kamath PS
在美国，酒精相关性肝病已成为肝移植的主要适应证，部分原因是高风险饮酒行为和酒精使用障碍（AUD）的患病率增加，尤其是在年轻女性中。持续戒酒不仅可能预防酒精相关性肝病的发生和进展，甚至在疾病晚期也可能导致临床症状显著改善。在这篇综述中，我们讨论酒精相关性肝病的诊断和门诊管理，重点是酒精使用障碍的治疗方案以及营养状况评估。
Alcohol-related liver disease has become the leading indication for liver transplantation in the US, partly due to an increase in the prevalence of high risk drinking behaviour and alcohol use disorder (AUD), particularly among young women. Achievement of sustained alcohol abstinence may not only prevent development and progression of alcohol-related liver disease, but may also lead to significant clinical improvement even in the advanced stages of disease. In this review, we discuss the diagnosis and outpatient management of alcohol-related liver disease with emphasis on treatment options for AUD and assessment of nutritional status.