Shifts in Food Preferences After Bariatric Surgery: Observational Reports and Proposed Mechanisms
Shifts in Food Preferences After Bariatric Surgery: Observational Reports and Proposed Mechanisms
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DOI：
10.1007/s13679-017-0270-y
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发表时间：
2017-09-01
影响因子：
8.8
通讯作者：
Docherty, Neil G.
中科院分区：
文献类型：
--
作者：
Kapoor, Natasha;Al-Najim, Werd;Docherty, Neil G.
减肥手术是目前治疗肥胖最有效的方法。 Roux-en-Y 胃绕道手术 (RYGB) 是最常进行的减肥手术，可实现长期体重减轻。食物偏好和选择的改变可能有助于 RYGB 的长期益处。本手稿回顾了记录 RYGB 后人类和实验动物食物偏好变化的现有文献，并讨论了有关相关潜在机制的当前理论。肥胖与对甜食和高脂肪食物的偏好增加有关，最一致的证据是 RYGB 后动物和人类研究中对这些热量密集食品的转变。自我报告是记录人类食物偏好的最常用方法，而更直接的方法已用于动物工作。这种方法论的异质性可能会导致不一致的结果。未来的人类研究应侧重于直接测量，以证实从动物研究中获得的机制见解。
Bariatric surgery is currently the most effective treatment for obesity. Roux-en-Y gastric bypass (RYGB) is the most commonly performed bariatric procedure and results in long-term weight loss. Alterations in food preference and choices may contribute to the long-term benefits of RYGB. This manuscript reviews the available literature documenting changes in food preference in both humans and experimental animals after RYGB and discusses the current theory on the underlying mechanisms involved.Obesity is associated with an increased preference for sweet and high-fat foods, and the most consistent evidence has been the shift away from these calorie-dense foods in both animal and human studies after RYGB. Self-reporting is the most common method used to record food preferences in humans, while more direct approaches have been used in animal work. This methodological heterogeneity may give rise to inconsistent findings.Future studies in humans should focus on direct measures to permit corroboration of mechanistic insights gained from animal studies.