Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: A Monte Carlo study
Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: A Monte Carlo study
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DOI：
10.1093/rpd/nci259
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发表时间：
2005-01-01
影响因子：
1
通讯作者：
Smith, AR
中科院分区：
文献类型：
--
作者：
Bues, M;Newhauser, WD;Smith, AR
在步进和发射点扫描中，小直径的质子束被磁扫描并改变能量以覆盖肿瘤。初步估计的束大小表明，额外的准直硬件将需要较低的能量质子束，以实现临床上可接受的横向剂量衰减的质子束的边缘。在这份报告中，我们提出了一个简单的多叶准直器，这表明这样的设备可以用来改善横向剂量下降的模型从蒙特卡罗模拟的剂量测定数据。研究了与该装置临床使用有关的剂量学量，包括侧半影、叶片透射和扇形效应。多叶准直与锐化横向剂量下降的差分点加权技术进行了比较。
In step and shoot spot-scanning, a small-diameter proton beam is magnetically swept and varied in energy in order to cover the tumour. Initial estimates of the beam size indicate that additional collimating hardware will be needed for lower energy proton beams in order to achieve a clinically acceptable lateral dose falloff at the edge of the proton beam. In this report, we present dosimetric data from Monte Carlo simulations with a model of a simple multileaf collimator which indicate that such a device may be used to improve the lateral dose falloff. The dosimetric quantities relevant to the clinical usefulness of the device are studied, including lateral penumbra, leaf transmission and scalloping effect. Multileaf collimation is compared with a differential spot-weighting technique of sharpening the lateral dose falloff.