Lipid droplets: size matters.
Lipid droplets: size matters.
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DOI：
10.1093/jmicro/dfr016
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发表时间：
2011-08
期刊：
影响因子：
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通讯作者：
Michitaka Suzuki;Yuki Shinohara;Y. Ohsaki;T. Fujimoto
中科院分区：
文献类型：
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作者：
Michitaka Suzuki;Yuki Shinohara;Y. Ohsaki;T. Fujimoto
脂滴（lipid droplet，LD）是广泛存在于从细菌到哺乳动物的各种生物体中的一种细胞器，已引起医学和细胞生物学领域的广泛关注。白色脂肪细胞中的LD通常被视为原型LD，但考虑到其大小、细胞内定位和分子组成与非脂肪细胞LD的那些有很大不同，LD是一个特殊的例子。这些差异赋予脂肪细胞和非脂肪细胞LD不同的特性。在这篇文章中，我们通过讨论脂肪细胞和非脂肪细胞LD之间的差异来解决目前对LD的理解。
The lipid droplet (LD), an organelle that exists ubiquitously in various organisms, from bacteria to mammals, has attracted much attention from both medical and cell biology fields. The LD in white adipocytes is often treated as the prototype LD, but is rather a special example, considering that its size, intracellular localization and molecular composition are vastly different from those of non-adipocyte LDs. These differences confer distinct properties on adipocyte and non-adipocyte LDs. In this article, we address the current understanding of LDs by discussing the differences between adipocyte and non-adipocyte LDs.