Exotic food allergy: anaphylactic reaction to lychee.
Exotic food allergy: anaphylactic reaction to lychee.
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DOI：
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发表时间：
2007
影响因子：
7.2
通讯作者：
Ulrike Raap;T. Schaefer;Alexander Kapp;Bettina Wedi
中科院分区：
文献类型：
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作者：
Ulrike Raap;T. Schaefer;Alexander Kapp;Bettina Wedi
文献中关于荔枝果过敏反应的报道很少。我们描述了一名 26 岁男性的病例，他在摄入荔枝果实后 15 分钟内出现瘙痒、全身性荨麻疹、嘴唇和舌头严重血管性水肿并伴有呼吸困难。尽管我们没有发现荔枝特异性免疫球蛋白 E 抗体，但对荔枝的嗜碱性粒细胞活化试验 (BAT) 和细胞抗原刺激试验 (CAST) 均呈阳性，新鲜荔枝果实的点刺试验也是如此。该患者还患有欧芹口腔食物过敏综合征，并对艾蒿过敏，但对乳胶或 profilin 不敏感。 BAT 和 CAST 是诊断异国食物过敏的有用工具。艾蒿被认为是导致该患者出现交叉反应的过敏原，因为他对乳胶或 profilin 没有过敏。
There are very few reports on allergic reactions to lychee fruit in the literature. We describe the case of a 26-year-old man who developed pruritus, generalized urticaria, and severe angioedema of his lips and tongue with dyspnea within 15 minutes after lychee fruit intake. Although we found no lychee-specific immunoglobulin E antibodies, a basophil activation test (BAT) and a cellular antigen stimulation test (CAST) to lychee were both positive, as was a prick-to-prick test with fresh lychee fruit. The patient also suffered from an oral food allergy syndrome to parsley and was sensitized to mugwort but not to latex or profilin. BAT and CAST are helpful tools in the diagnostic workup for exotic food allergy. Mugwort is suggested as the allergen responsible for,the cross-reactivity presented by this patient, as he had no sensitization to latex or profilin.