Fatigue in multiple sclerosis presenting as acute relapse: subjective and objective assessment

Fatigue in multiple sclerosis presenting as acute relapse: subjective and objective assessment
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DOI:
10.1177/1352458507082480
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发表时间:
2008-03-01
期刊:
MULTIPLE SCLEROSIS
影响因子:
--
通讯作者:
Meissner, Heike
Meissner, Heike
中科院分区:
其他
文献类型:
--
作者:
Flachenecker, Peter;Meissner, Heike

文献摘要

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我们报道了一名多发性硬化症 (MS) 患者,其症状是疲劳,这是 MS 急性复发的唯一表现。疲劳通过“维尔茨堡多发性硬化症疲劳量表(WEIMuS)”量表进行评估,并通过注意力的神经心理学测试进行确认。经过大剂量皮质类固醇治疗后,主观症状完全消失。 WEIMuS 评分和神经心理学测试都证实了这一改善。多发性硬化症相关的疲劳可能是多发性硬化症急性复发的唯一症状,神经心理学方法可用于客观评估和跟踪这种常见且致残症状的时间进程。
We report on a patient with multiple sclerosis ( MS) who presented with fatigue as the only manifestation of an acute MS relapse. Fatigue was assessed by the 'Wurzburg Fatigue Inventory in MS ( WEIMuS)' scale and confirmed by neuropsychological testing of attention. After high- dose corticosteroid therapy, subjective symptoms were completely abolished. The improvement was corroborated by both, the WEIMuS score and neuropsychological testing. MS- related fatigue may be the only symptom of an acute MS relapse, and neuropsychological methods may be used to objectively assess and follow the time course of this common and disabling symptom.