ONTOGENY OF CHORDA TYMPANI NERVE RESPONSES TO GUSTATORY STIMULI IN THE RAT
ONTOGENY OF CHORDA TYMPANI NERVE RESPONSES TO GUSTATORY STIMULI IN THE RAT
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DOI：
10.1016/0006-8993(80)90432-1
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发表时间：
1980-01-01
期刊：
影响因子：
2.9
通讯作者：
ALMLI, CR
中科院分区：
文献类型：
--
作者：
HILL, DL;ALMLI, CR
记录了2 - 110日龄大鼠鼓索神经（CT）对施加于舌背表面的化学刺激（0.5 M氯化钠、0.5 M氯化锂、0.5 M氯化铵和0.1 M柠檬酸）的电活动（全神经反应）。仅2日龄大鼠的鼓索神经对各种化学刺激有不同的反应。在20 - 34日龄以及35 - 90日龄之间，鼓索神经对0.5 M氯化钠和0.5 M氯化锂相对于0.5 M氯化铵的反应性增强。鼓索神经对0.1 M柠檬酸相对于0.5 M氯化铵的反应性在6 - 19日龄时增强，然后降低至成年期。一系列不同浓度的氯化铵溶液（0.1 M、0.25 M、0.5 M和1.0 M）显示，6 - 110日龄大鼠的鼓索神经随着氯化铵浓度的增加，反应幅度增大。鼓索神经对舌的机械和热刺激有反应。这种反应性在整个发育过程中基本不变。显然，仅2日龄大鼠的鼓索神经对施加于舌的化学刺激有不同反应，并且鼓索神经对化学刺激的反应性在发育过程中发生变化。
Electrical activity (whole-nerve responses) of the chorda tympani nerve (CT) in rats at 2-110 days old was recorded in response to chemical (0.5 M NaCl, 0.5 M LiCl, 0.5 M NH4Cl and 0.1 M citric acid) stimuli applied to the dorsal surface of the tongue. The CT of rats only 2 days old was differentially responsive to the various chemical stimuli. The responsiveness of the CT to 0.5 M NaCl and 0.5 M LiCl relative to 0.5 M NH4Cl increased between 20-34 days old and again between 35-90 days old. The responsiveness of the CT to 0.1 M citric acid relative to 0.5 M NH4Cl increased from 6-19 days old, then decreased to adulthood. A concentration series of NH4Cl solutions (0.1 M, 0.25 M, 0.5 M and 1.0 M) revealed that the CT of rats 6-110 days old displayed increased response magnitudes as the concentration of NH4Cl increased. The CT was responsive to mechanical and thermal stimulation of the tongue. This responsiveness was essentially unchanged throughout development. The CT of rats only 2 days old apparently is differentially responsive to chemical stimuli applied to the tongue and CT responsiveness to chemical stimuli changes during development.