A longitudinal study on influence of primary facial deformities on maxillofacial growth in patients with cleft lip and palate
A longitudinal study on influence of primary facial deformities on maxillofacial growth in patients with cleft lip and palate
复制标题
DOI：
10.1597/03-151.1
复制
发表时间：
2005-11-01
期刊：
影响因子：
--
通讯作者：
Ohishi, M
中科院分区：
文献类型：
--
作者：
Nakamura, N;Suzuki, A;Ohishi, M
目的：本研究的目的是利用三维（3D）分析方法对单侧唇腭裂（UCLP）患儿的原发性面部畸形进行特征描述，并对婴儿期至青春期面部畸形与颌面发育的关系进行序列分析。对象：选取21例日本单侧唇裂伴牙槽畸形（UCLA）患者和20例单侧唇裂伴牙槽畸形（UCLP）患者进行手术并随访15年以上。主要观察指标：采用三维激光扫描仪对面部整形模型进行扫描。追踪15岁或以上受试者的侧位脑电图，并计算线性和角度测量值。分析了青少年初级面部形态与颌面部形态的相关性。结果：三维分析显示，与UCLA相比，UCLP组的眼远视更大，眼裂更宽，鼻梁基底偏曲更大，鼻翼基底后移更严重。UCLP组的上唇总表面积明显小于UCLA组。相关分析显示，唇裂宽度、鼻小柱基底偏度、鼻基底宽度差值、上唇表面积与上颌长度、上颌牙槽基底前侧位置、面部后侧高度、下颌骨高角均有统计学相关性。结论：面部畸形程度越轻、上唇组织体积越大的患者，其颌面生长越好。
Objective: The goal of this study was to use three-dimensional (3D) analysis to characterize the primary facial deformities in children with unilateral cleft lip and palate (UCLP) and then serially analyze the relationships between facial deformities and maxillofacial growth from infancy to adolescence.Participants: Twenty-one Japanese subjects with unilateral cleft lip and alveolus (UCLA) and 20 with UCLP who had been operated on and then followed up for more than 15 years were enrolled in this study.Main Outcome Measures: Facial cast models taken at cheiloplasty were scanned with a 3D laser scanner. Lateral cephalographs taken when subjects were 15 years of age or older were traced, and linear and angular measurements were calculated. The correlation between primary facial forms and maxillofacial morphology in adolescence was analyzed.Results: Three-dimensional analysis showed larger ocular hypertelorism, wider cleft, greater deviation of the columella base, and more severe retruded position of the affected nasal alar base in subjects with UCLP than those with UCLA. Total surface area of the upper lips in subjects with UCLP was significantly smaller than those with UCLA. Correlation analyses revealed that the width of cleft lip, deviation of the columella base, difference of the nose base width, and surface area of the upper lip were statistically correlated with the maxillary length, the anterior position of the maxillary alveolar base, the posterior facial height, and the high angle of the mandible.Conclusion: The subjects who had less severe facial deformities and more tissue volume of the upper lips at cheiloplasty showed better maxillofacial growth.