Dermal Peptide Delivery Using Colloidal Carrier Systems
Dermal Peptide Delivery Using Colloidal Carrier Systems
复制标题
使用胶体载体系统进行真皮肽输送
DOI：
10.1159/000109082
复制
发表时间：
2007
影响因子：
2.7
通讯作者：
R. Neubert
中科院分区：
文献类型：
--
作者：
Alexandra S. B. Goebel;R. Neubert
The advancement in synthetic and molecular biology techniques over the past years has resulted in the application of peptides or peptide-like drugs becoming a growing field in therapeutics. Because of the unfavorable chemical properties of peptides, it poses a challenge to find an optimized way of drug administration. The transdermal route has attracted interest as a promising way to advance the delivery of these drugs. The objective of this review is to summarize the level of research of microemulsions as colloidal carrier for dermal peptide drug delivery. The presented studies resulted in enhanced drug delivery or superior penetration profiles of peptides incorporated in microemulsions in comparison to conventional vehicles. Due to their benefits like high solubilization capacity, enhanced drug delivery, noninvasive administration or easy preparation, microemulsions offer a suitable vehicle for dermal and transdermal drug delivery.
使用脂质增强电穿孔进行透皮胰岛素递送。
DOI：
10.1016/s0005-2736(02)00453-4
发表时间：
2002
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Sen,Arindam;Daly,MeganE;Hui,SekWen
通讯作者：
Hui,SekWen