Effect of behavior therapy for Tourette's disorder on psychiatric symptoms and functioning in adults.
Effect of behavior therapy for Tourette's disorder on psychiatric symptoms and functioning in adults.
复制标题
抽动秽语症行为疗法对成人精神症状和功能的影响。
DOI：
10.1017/s0033291719002150
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发表时间：
2020
影响因子：
6.9
通讯作者：
Peterson,AlanL
中科院分区：
文献类型：
--
作者：
McGuire,JosephF;Ricketts,EmilyJ;Scahill,Lawrence;Wilhelm,Sabine;Woods,DouglasW;Piacentini,John;Walkup,JohnT;Peterson,AlanL
虽然行为疗法降低了抽动的严重程度，但尚不清楚行为疗法是否能改善成人抽动症患者的精神症状和功能结果。这些信息对于有效的治疗计划是必不可少的。本研究探讨行为疗法对老年青少年和成人抽动障碍患者的精神症状和功能结局的影响。方法对122例TD或慢性抽动障碍患者进行临床试验，比较行为疗法与心理教育和支持疗法的差异。在基线、治疗后和随访中，参与者完成了抽动严重程度、共生症状(注意力不集中、冲动、多动、愤怒、焦虑、抑郁、强迫和心理社会功能)和心理社会功能的评估。我们通过重复测量和单因素方差分析比较了抽动严重程度、精神症状和功能结果的变化。结果在治疗后，接受行为治疗的参与者报告说，在6个月的随访中，与接受支持治疗的参与者相比，接受行为治疗的参与者报告的强迫症状的减少更多(=0.39-0.42，p<；0.03-0.04)。结论行为治疗在短期内对共存的强迫症状具有治疗优势，并随着时间的推移降低抽动的严重程度和残疾。可能有必要进行额外的治疗，以解决共存症状和改善功能结果。
BackgroundAlthough behavior therapy reduces tic severity, it is unknown whether it improves co-occurring psychiatric symptoms and functional outcomes for adults with Tourette's disorder (TD). This information is essential for effective treatment planning. This study examined the effects of behavior therapy on psychiatric symptoms and functional outcomes in older adolescents and adults with TD.MethodA total of 122 individuals with TD or a chronic tic disorder participated in a clinical trial comparing behavior therapy to psychoeducation and supportive therapy. At baseline, posttreatment, and follow-up visits, participants completed assessments of tic severity, co-occurring symptoms (inattention, impulsiveness, hyperactivity, anger, anxiety, depression, obsessions, and compulsions), and psychosocial functioning. We compared changes in tic severity, psychiatric symptoms, and functional outcomes using repeated measure and one-way analysis of variance.ResultsAt posttreatment, participants receiving behavior therapy reported greater reductions in obsessions compared to participants in supportive therapy ( = 0.39–0.42, p < 0.03–0.04) at the 6-month follow-up.ConclusionBehavior therapy has a therapeutic benefit for co-occurring obsessive symptoms in the short-term, and reduces tic severity and disability in adults with TD over time. Additional treatments may be necessary to address co-occurring symptoms and improve functional outcomes.