PROMOTER OF A EUKARYOTIC TRANSFER-RNA PRO GENE IS COMPOSED OF 3 NON-CONTIGUOUS REGIONS

PROMOTER OF A EUKARYOTIC TRANSFER-RNA PRO GENE IS COMPOSED OF 3 NON-CONTIGUOUS REGIONS
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DOI:
10.1073/pnas.79.4.1195
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发表时间:
1982-01-01
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子:
--
通讯作者:
CORTESE, R
CORTESE, R
中科院分区:
其他
文献类型:
--
作者:
CILIBERTO, G;CASTAGNOLI, L;CORTESE, R

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秀丽隐杆线虫tRNApro基因的71个碱基对编码序列包含了注射卵母细胞中转录和加工所需的所有信息。构建了几个编码tRNAPro的DNA亚克隆,携带缺失或插入,或两者兼而有之。它们的转录特性导致了这样的假设:tRNAPro基因启动子由编码序列内的3个不连续区域组成。
The 71-base-pair coding sequence of the tRNApro gene from Caenorhabditis elegans contains all of the information required for transcription and processing in the injected oocytes. Several subclones of the DNA coding for the tRNAPro were constructed, carrying deletions or insertions, or both. Their transcriptional properties lead to the hypothesis that the tRNAPro gene promoter is composed of 3 discontinuous regions within the coding sequence.