Pancreas cancer and smoking, beverage consumption, and past medical history.
Pancreas cancer and smoking, beverage consumption, and past medical history.
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DOI：
10.1093/jnci/76.1.49
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
T. Mack;M. Yu;R. Hanisch;B. Henderson
中科院分区：
文献类型：
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作者：
T. Mack;M. Yu;R. Hanisch;B. Henderson
将代表洛杉矶县工作年龄居民确诊病例的 490 名胰腺癌患者与按年龄、性别、种族和社区进行匹配的健康对照进行比较。对职业、吸烟、食品和饮料消费以及病史进行了家庭访谈。吸烟是胰腺癌发生的强烈且一致的预测因素；不吸烟十年后，这种影响就消失了，并且当前吸烟者的风险并没有随着每日剂量的增加而增加。胰腺癌与过去饮用茶、碳酸饮料、啤酒或烈酒之间没有联系；并且与咖啡消费的关联不一致。胰腺癌与过去任何时间的胃次全切除史之间的密切相关性不能用偶然或任何其他因素来解释。胰腺癌患者经历的任何类型的过敏都较少。
Four hundred and ninety pancreas cancer patients representative of confirmed cases in Los Angeles County residents of working age were compared to healthy controls individually matched by age, sex, race, and neighborhood. Home interviews were conducted on occupation, smoking, food and beverage consumption, and medical history. Cigarette smoking was a strong and consistent predictor of pancreas cancer occurrence; the effect disappeared after a decade of nonsmoking, and there was no increase in risk among current smokers as daily dose increased. There was no link between pancreas cancer and past consumption of tea, carbonated beverages, beer, or spirits; and an association with coffee consumption was inconsistent. A strong association between pancreas cancer and history of subtotal gastrectomy at any past time could not be explained by chance or any other factor. Pancreas cancer patients had experienced fewer allergies of any kind.