Association of antigenic type of Herpesvirus hominis with site of viral recovery.
Association of antigenic type of Herpesvirus hominis with site of viral recovery.
复制标题
人疱疹病毒抗原类型与病毒恢复部位的关联。
作者：
W. Dowdle;A. Nahmias;Rebecca W. Harwell;F. P. Pauls
通过微量子中和技术对从代表不同临床表现的多个地点分离的九十一个人型嗜血杆菌菌株进行了针对先前测定的代表疱疹病毒的两种抗原类型的抗血清的测试。病毒分离株可分为两个不同的组，每个组的分布与代表 1 型或 2 型的对照病毒相似。所有 42 种被鉴定为 2 型的病毒株均从与成人生殖道受累直接或间接相关的疱疹感染中分离出来。其余 49 株菌株被鉴定为 1 型，代表所有其他部位，包括与脑膜脑炎、疱疹湿疹、皮炎（大腿和臀部除外）、龈口炎、无症状疱疹和唇疱疹相关的病毒。疱疹病毒的特定抗原类型与生殖道或密切相关部位的关联具有特殊的生物学和流行病学意义，并表明病毒类型具有特定的趋向性。
Ninety-one H. hominis strains isolated from a variety of sites representing various clinical manifestations were tested by the micro-quantal neutralization technique against antisera determined previously to represent two antigenic types of herpesvirus. The virus isolates could be divided into two distinct groups each with a distribution similar to that of a control virus representing type 1 or type 2. All 42 strains identified as type 2 were isolated from herpetic infections related directly or indirectly to involvement of the adult genital tract. The remaining 49 strains, identified as type 1, represented all other sites and included viruses associated with meningoencephalitis, eczema herpeticum, dermatitis (other than on thigh and buttocks), gingivostomatitis, asymptomatic herpes and herpes labialis. The association of a particular antigenic type of herpesvirus to the genital tract, or closely related sites, is of particular biologic and epidemiologic interest and suggests a specific tropism of a virus type.