SUPPRESSION OF AUDITORY NERVE ACTIVITY BY STIMULATION OF EFFERENT FIBERS TO COCHLEA
SUPPRESSION OF AUDITORY NERVE ACTIVITY BY STIMULATION OF EFFERENT FIBERS TO COCHLEA
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DOI：
10.1152/jn.1956.19.5.424
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发表时间：
1956-01-01
影响因子：
2.5
通讯作者：
GALAMBOS, R
中科院分区：
文献类型：
--
作者：
GALAMBOS, R
方法本研究共使用51只猫。大多数用丁氨酸二乙酯(75毫克/公斤)、硝酸乙酯(60毫克/公斤)、乙醚-咖喱和乙醚去大脑制剂麻醉，当尝试时，也产生了类似的结果。手术程序开始于气管插管，然后反射头部和颈部的肌肉，以便能够隔离双侧外耳道，并清楚地看到两个大疱处。然后切开每个耳道，并将一根连接着耳机的铜管插入其中。当调整时，这些管子都像Horsley-Clarke仪器的耳塞一样固定头部，并允许从耳机到耳膜的清晰声音路径。然后打开每个灯泡，以露出圆形窗户。上面放了一根银线。然后切除小脑上方的枕骨，抽出足够的小脑，露出第四脑室底部，机械手控制的电击电极在第四脑室底部刻度1 mm。台阶，都放好了。
METHODA total of 51 cats was used in this study. Most were anesthetized with Dial-urethane (75 mg./kg.); Nembutal (60 mg./kg.), ether-curare, and ether-decerebrate preparations, when tried, yielded similar results. Operative procedures began with tracheal cannulation followed by reflection of the muscles of the head and neck to permit bilateral isolation of the external auditory meatus and a clear view of both bullas. Each meatus was then cut across and a brass tube to which an earphone was attached inserted into it. These tubes, when adjusted, both held the head fixed as do the earplugs of a Horsley-Clarke apparatus, and permitted a clear sound path from earphone to eardrum. Each bulla was then opened so as to expose the round window,. upon which a silver wire was placed. The occipital bone over the cerebellum was then removed and sufficient cerebellum suctioned out to reveal the floor of the fourth ventricle upon which the shock electrodes, controlled by a manipulator graduated in 1 mm. steps, were placed.