Is bacterial tracheitis changing? A 14-month experience in a pediatric intensive care unit.
Is bacterial tracheitis changing? A 14-month experience in a pediatric intensive care unit.
复制标题
细菌性气管炎有变化吗？
DOI：
10.1086/514681
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
B. Jacobs
中科院分区：
文献类型：
--
作者：
Tamar Bernstein;R. Brilli;B. Jacobs
细菌性气管炎的特征是急性上呼吸道阻塞和气管内的脓性分泌物。以往，受影响的儿童年龄小，喘鸣，中毒出现，需要气管插管，发病率和死亡率是显着的。金黄色葡萄球菌是最常见的微生物。在这项回顾性研究的14个月期间，46名儿童因此诊断而入住儿科重症监护室，并对他们的病历进行了审查。与以前的报告相比，本研究中的儿童年龄较大（平均值+/-平均值的标准误[SEM]，69.3 +/- 6.8个月），毒性较低。46例患者中只有26例（57%）需要气管插管。插管患者明显比未插管患者年轻（平均值+/- SEM，46.9 +/- 6.5 vs 98.9 +/- 9.9个月）。在45个细菌呼吸道培养物中的12个（27%）中鉴定出卡他莫拉菌，而在25个病毒呼吸道培养物中的18个（72%）中回收到甲型流感病毒。无严重并发症。该系列代表了最大的报告队列的患者与这种情况，并表明流行病学的变化，朝着一个较低的病态。
Bacterial tracheitis is characterized by acute upper-airway obstruction and purulent secretions within the trachea. Historically, affected children were young, stridorous, and toxic-appearing and required tracheal intubation, and morbidity and mortality were significant. Staphylococcus aureus was the most common organism involved. During the 14 months of this retrospective study, 46 children were admitted to the pediatric intensive care unit because of this diagnosis, and their medical records were reviewed. Compared with those in previous reports, children in this study were older (mean +/- standard error of the mean [SEM], 69.3 +/- 6.8 months) and less toxic. Only 26 (57%) of 46 patients required tracheal intubation. Intubated patients were significantly younger than nonintubated patients (mean +/- SEM, 46.9 +/- 6.5 vs. 98.9 +/- 9.9 months). Moraxella catarrhalis was identified in 12 (27%) of 45 bacterial respiratory cultures, while influenza A virus was recovered from 18 (72%) of 25 viral respiratory cultures. There were no major complications. This series represents the largest reported cohort of patients with this condition and suggests an epidemiological change toward a less morbid condition.